Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.49 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | MPO | P05164 | 1/20 | 0.40 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.40 |
| ▸ | DAO | P14920 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.39 |
| ▸ | FYN | P06241 | 1/20 | 0.39 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13824308 | 0.83 | EGLN1 (0.42) | HTR6HTR2CHTR2BSLC5A2EGLN1 | |
| SCHEMBL13823965 | 0.81 | EGLN1 (0.45) | HTR6EGLN1MEN1KMT2A | |
| SCHEMBL13727990 | 0.80 | HTR6 (0.41) | HTR6HTR2CHTR2BTAAR1LTA4H | |
| SCHEMBL15592673 | 0.79 | EGLN1 (0.41) | HTR6EGLN1MEN1KMT2A | |
| SCHEMBL13728722 | 0.78 | HTR6 (0.44) | HTR6HTR2CHTR2BLTA4HIDO1 | |
| SCHEMBL13729492 | 0.77 | CALM1 (0.46) | HTR6MEN1KMT2A | |
| SCHEMBL31037849 | 0.76 | DHPS (0.49) | HTR6ACHEMEN1TP53KMT2A | |
| SCHEMBL17721729 | 0.76 | HTR6 (0.46) | HTR6HTR2CHTR2BTAAR1LTA4H | |
| SCHEMBL13731334 | 0.76 | HTR2C (0.47) | HTR2CHTR2BTAAR1LTA4HIDO1 | |
| SCHEMBL30000562 | 0.74 | TAAR1 (0.60) | TAAR1LTA4HIDO1SLC5A2DAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012151567-A1 | PYRIMIDINONE COMPOUNDS AND METHODS FOR PREVENTING AND TREATING INFLUENZA | ST. JUDE CHILDREN'S RESEARCH HOSPITAL (US) | 2012-11-08 | — | — | WO | disclosed |