Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 5/20 | 0.40 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13729857 | 0.81 | PARP1 (0.40) | PARP1PARP2 | |
| SCHEMBL22720412 | 0.76 | PARP1 (0.42) | PARP1PARP2 | |
| SCHEMBL22720477 | 0.74 | MEN1 (0.39) | PARP1PARP2 | |
| SCHEMBL30103427 | 0.68 | PLAU (0.43) | — | |
| SCHEMBL13017574 | 0.66 | ALDH1A1 (0.41) | — | |
| SCHEMBL28227905 | 0.65 | PARP1 (0.55) | PARP1PARP2 | |
| SCHEMBL10002467 | 0.65 | ALDH1A1 (0.50) | — | |
| SCHEMBL6644584 | 0.65 | PARP1 (0.49) | PARP1PARP2 | |
| SCHEMBL30751437 | 0.64 | PARP1 (0.51) | PARP1PARP2 | |
| SCHEMBL38663601 | 0.64 | PLAU (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020239123-A1 | AROMATIC HETEROCYCLIC DERIVATIVE MODULATOR AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海翰森生物医药科技有限公司 | 2020-12-03 | — | — | WO | disclosed |