Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | CASP1 | P29466 | 3/20 | 0.44 |
| ▸ | CASP7 | P55210 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 2/20 | 0.44 |
| ▸ | PPARG | P37231 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 2/20 | 0.44 |
| ▸ | BLM | P54132 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.44 |
| ▸ | NCOA2 | Q15596 | 2/20 | 0.44 |
| ▸ | NCOA1 | Q15788 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10919684 | 0.70 | L3MBTL1 (0.36) | ALDH1A1CASP1CASP7HSD17B10L3MBTL1 | |
| SCHEMBL2315915 | 0.67 | MAPT (0.45) | ALDH1A1CASP1CASP7HSD17B10L3MBTL1 | |
| SCHEMBL2315920 | 0.67 | MAPT (0.45) | ALDH1A1CASP1CASP7HSD17B10L3MBTL1 | |
| SCHEMBL23643407 | 0.67 | ALDH1A1 (0.35) | ALDH1A1MEN1POLBKMT2A | |
| SCHEMBL13732723 | 0.67 | KMT2A (0.44) | ALDH1A1MEN1POLBMAPTKMT2A | |
| SCHEMBL10501153 | 0.67 | MAPT (0.35) | ALDH1A1CASP1CASP7HSD17B10L3MBTL1 | |
| SCHEMBL11034647 | 0.65 | L3MBTL1 (0.43) | ALDH1A1CASP1CASP7HSD17B10L3MBTL1 | |
| SCHEMBL18655702 | 0.63 | L3MBTL1 (0.41) | ALDH1A1CASP1CASP7HSD17B10L3MBTL1 | |
| SCHEMBL14714137 | 0.61 | L3MBTL1 (0.37) | ALDH1A1CASP1CASP7HSD17B10L3MBTL1 | |
| SCHEMBL6850987 | 0.58 | GSK3A (0.44) | ALDH1A1HSD17B10L3MBTL1HPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2699090-A1 | 3,4-DISUBSTITUTED PYRROLE 2,5-DIONES AND THEIR USE AS FUNGICIDES | BASF SE (DE) | 2014-02-26 | — | — | EP | disclosed |
| US-20140045689-A1 | 3,4-disubstituted pyrrole 2,5-diones and their use as fungicides | BASF SE (DE) | 2014-02-13 | — | — | US | disclosed |
| WO-2012143468-A1 | 3,4-DISUBSTITUTED PYRROLE 2,5-DIONES AND THEIR USE AS FUNGICIDES | BASF SE (DE) | 2012-10-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140045689-A1 | 3,4-disubstituted pyrrole 2,5-diones and their use as fungicides | CYP51A1, DDT, DPM1 | ALDH1A1 520/4885CASP1 446/4885CASP7 655/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.