Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10919684 | 0.70 | L3MBTL1 (0.36) | MAPTMEN1ALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL13733297 | 0.67 | ALDH1A1 (0.44) | MAPTMEN1ALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL11034647 | 0.65 | L3MBTL1 (0.43) | MAPTMEN1ALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL27960232 | 0.64 | PRMT1 (0.33) | MAPTALDH1A1THRBTDP1PRMT1 | |
| SCHEMBL29562301 | 0.64 | CASP3 (0.38) | MAPTALDH1A1KDM4EPOLBHPGD | |
| SCHEMBL10500977 | 0.64 | ALOX15 (0.36) | MAPTMEN1ALDH1A1KMT2AKDM4E | |
| SCHEMBL18655702 | 0.63 | L3MBTL1 (0.41) | MAPTMEN1ALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL17986800 | 0.62 | MEN1 (0.39) | MAPTMEN1KMT2AL3MBTL1GAA | |
| SCHEMBL14714137 | 0.61 | L3MBTL1 (0.37) | MAPTMEN1ALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL6850987 | 0.58 | GSK3A (0.44) | MAPTMEN1ALDH1A1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0152759-B1 | AMINOISOTHIAZOLE COMPOUNDS | BASF Aktiengesellschaft (DE) | 1989-08-23 | — | — | EP | disclosed |
| US-4785116-A | Aminoisothiazole compounds | BASF AKTIENGESELLSCHAFT (DE) | 1988-11-15 | — | — | US | disclosed |
| EP-0086389-B1 | AMINOPYRAZOLE COMPOUNDS | BASF Aktiengesellschaft (DE) | 1986-12-10 | — | — | EP | disclosed |
| EP-0152759-A1 | Aminoisothiazole compounds | BASF Aktiengesellschaft (DE) | 1985-08-28 | — | — | EP | disclosed |
| US-4490541-A | 5(3)-Aminopyrazolo-3,4(4,5)-dicarboximide azo dyestuff intermediates | BASF AKTIENGESELLSCHAFT (DE) | 1984-12-25 | — | — | US | disclosed |
| EP-0086389-A2 | Aminopyrazole compounds | BASF Aktiengesellschaft (DE) | 1983-08-24 | — | — | EP | disclosed |