Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 11/20 | 0.41 |
| ▸ | KLKB1 | P03952 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | F11 | P03951 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20055477 | 0.83 | KLKB1 (0.36) | DGAT1KLKB1 | |
| SCHEMBL13734316 | 0.83 | DGAT1 (0.58) | DGAT1KLKB1F11 | |
| SCHEMBL692594 | 0.80 | DGAT1 (0.45) | DGAT1KLKB1MAPTNPC1 | |
| SCHEMBL13734146 | 0.79 | DGAT1 (0.40) | DGAT1KLKB1MAPTNPC1F11 | |
| SCHEMBL205729 | 0.78 | ALDH1A1 (0.41) | MAPT | |
| SCHEMBL2706305 | 0.78 | ALDH1A1 (0.41) | MAPT | |
| SCHEMBL13732158 | 0.78 | DGAT1 (0.39) | DGAT1KLKB1MAPTNPC1 | |
| SCHEMBL27094134 | 0.78 | DGAT1 (0.39) | DGAT1KLKB1MAPTNPC1 | |
| SCHEMBL16330879 | 0.78 | DGAT1 (0.39) | DGAT1KLKB1MAPTNPC1F11 | |
| SCHEMBL17592021 | 0.78 | DGAT1 (0.44) | DGAT1KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2699561-B1 | ANDROGEN RECEPTOR MODULATING CARBOXAMIDES | ORION CORP (FI) | 2015-06-03 | — | — | EP | disclosed |
| US-8921378-B2 | Androgen receptor modulating carboxamides | ORION CORPORATION (FI) | 2014-12-30 | — | — | US | disclosed |
| EP-2699561-A1 | ANDROGEN RECEPTOR MODULATING CARBOXAMIDES | Orion Corporation (FI) | 2014-02-26 | — | — | EP | disclosed |
| WO-2012143599-A1 | ANDROGEN RECEPTOR MODULATING CARBOXAMIDES | ORION CORPORATION (FI) | 2012-10-26 | — | — | WO | disclosed |