Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 1/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 8/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.31 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16105980 | 0.83 | TAAR1 (0.36) | DGAT1TAAR1 | |
| SCHEMBL16105981 | 0.83 | TAAR1 (0.36) | DGAT1TAAR1 | |
| SCHEMBL13733342 | 0.83 | DGAT1 (0.41) | KLKB1DGAT1 | |
| SCHEMBL15368135 | 0.82 | DGAT1 (0.40) | DGAT1TAAR1 | |
| Hydrochloric Acid SCHEMBL2813401 | 0.82 | TAAR1 (0.35) | DGAT1TAAR1 | |
| Hydrochloric Acid SCHEMBL535924 | 0.74 | L3MBTL1 (0.34) | DGAT1TAAR1 | |
| SCHEMBL2706305 | 0.74 | ALDH1A1 (0.41) | — | |
| SCHEMBL205729 | 0.74 | ALDH1A1 (0.41) | — | |
| SCHEMBL692594 | 0.74 | DGAT1 (0.45) | KLKB1DGAT1 | |
| SCHEMBL16144076 | 0.73 | GRM1 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3309157-A1 | ANTIVIRAL COMPOUNDS | Gilead Pharmasset LLC (US) | 2018-04-18 | — | — | EP | disclosed |