Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13733393 | 0.85 | UCHL1 (0.36) | XIAPBIRC2 | |
| SCHEMBL13733175 | 0.79 | XIAP (0.37) | XIAPBIRC2 | |
| SCHEMBL13733640 | 0.77 | XIAP (0.50) | XIAPBIRC2 | |
| SCHEMBL13733437 | 0.76 | XIAP (0.36) | XIAPBIRC2 | |
| SCHEMBL13732435 | 0.69 | XIAP (0.56) | XIAPBIRC2 | |
| SCHEMBL13732026 | 0.68 | XIAP (0.64) | XIAPBIRC2 | |
| SCHEMBL13733056 | 0.67 | NR1H2 (0.38) | XIAPBIRC2 | |
| SCHEMBL13732143 | 0.66 | XIAP (0.54) | XIAPBIRC2 | |
| SCHEMBL31725766 | 0.65 | NOTUM (0.44) | — | |
| Hydrochloric Acid SCHEMBL15649416 | 0.64 | XIAP (0.36) | XIAPBIRC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2699562-A1 | BICYCLIC HETEROCYCLE COMPOUNDS AND THEIR USES IN THERAPY | Astex Therapeutics Limited (GB) | 2014-02-26 | — | — | EP | disclosed |
| WO-2012143726-A1 | BICYCLIC HETEROCYCLE COMPOUNDS AND THEIR USES IN THERAPY | ASTEX THERAPEUTICS LIMITED (GB) | 2012-10-26 | — | — | WO | disclosed |