⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20298564 | 0.82 | CHRNB2 (0.34) | — | |
| SCHEMBL20298601 | 0.82 | CHRNB2 (0.34) | — | |
| Hydrochloric Acid SCHEMBL20298582 | 0.80 | CHRNB2 (0.33) | — | |
| SCHEMBL29497583 | 0.79 | — | — | |
| SCHEMBL18705654 | 0.76 | CHRNB2 (0.62) | — | |
| SCHEMBL19456202 | 0.76 | — | — | |
| SCHEMBL15819325 | 0.74 | CHRNB2 (0.38) | — | |
| SCHEMBL19948600 | 0.74 | CHRNB2 (0.61) | — | |
| SCHEMBL21543557 | 0.74 | CHRNB2 (0.38) | — | |
| SCHEMBL1404444 | 0.74 | CHRNB2 (0.61) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114269725-B | Anti-influenza virus compound, preparation method and application thereof | 西藏海思科制药有限公司 | 2024-09-17 | — | — | CN | disclosed |
| EP-4395892-A1 | COMPOUNDS AND METHODS FOR MODULATING SPLICING | Remix Therapeutics Inc. (US) | 2024-07-10 | — | — | EP | disclosed |
| US-20140066369-A1 | Modulators Of The GPR119 Receptor And The Treatment Of Disorders Related Thereto | ARENA PHARMACEUTICALS, INC. (US) | 2014-03-06 | — | — | US | disclosed |
| WO-2012145361-A1 | MODULATORS OF THE GPR119 RECEPTOR AND THE TREATMENT OF DISORDERS RELATED THERETO | ARENA PHARMACEUTICALS, INC. (US) | 2012-10-26 | — | — | WO | disclosed |