⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13733916 | 0.79 | — | — | |
| SCHEMBL3570524 | 0.75 | CHRNB2 (0.38) | — | |
| SCHEMBL3291228 | 0.75 | CHRNB2 (0.38) | — | |
| SCHEMBL2835362 | 0.75 | CHRNB2 (0.38) | — | |
| SCHEMBL3832372 | 0.73 | — | — | |
| Hydrochloric Acid SCHEMBL25345451 | 0.73 | CHRNB2 (0.36) | — | |
| SCHEMBL3061000 | 0.72 | MBTD1 (0.39) | — | |
| SCHEMBL653248 | 0.72 | MBTD1 (0.39) | — | |
| SCHEMBL653249 | 0.72 | MBTD1 (0.39) | — | |
| SCHEMBL18190538 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12180215-B2 | Substituted pyrrolo[3,4-d]imidazoles as JAK inhibitors | HENAN MEDINNO PHARMACEUTICAL TECHNOLOGY CO., LTD. (CN) | 2024-12-31 | — | — | US | disclosed |
| EP-3932919-B1 | JAK INHIBITOR COMPOUND AND USE THEREOF | HENAN MEDINNO PHARMACEUTICAL TECH CO LTD (CN) | 2024-06-26 | — | — | EP | disclosed |
| US-20230201165-A1 | JAK INHIBITOR COMPOUND FOR TREATING SEVERE PNEUMONIA | HENAN MEDINNO PHARMACEUTICAL TECHNOLOGY CO., LTD. (CN) | 2023-06-29 | — | — | US | disclosed |
| US-20230192711-A1 | JAK INHIBITOR COMPOUND AND USE THEREOF | HENAN MEDINNO PHARMACEUTICAL TECHNOLOGY CO., LTD. (CN) | 2023-06-22 | — | — | US | disclosed |
| US-11629148-B2 | Substituted pyrrolo[3,4-d]imidazoles as JAK inhibitors | HENAN MEDINNO PHARMACEUTICAL TECHNOLOGY CO., LTD. (CN) | 2023-04-18 | — | — | US | disclosed |
| US-20220073524-A1 | JAK INHIBITOR COMPOUND AND USE THEREOF | HENAN MEDINNO PHARMACEUTICAL TECHNOLOGY CO., LTD. (CN) | 2022-03-10 | — | — | US | disclosed |