Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT6A | Q92794 | 4/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.41 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.41 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.41 |
| ▸ | F10 | P00742 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | MPI | P34949 | 1/20 | 0.39 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.38 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.38 |
| ▸ | CETP | P11597 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13733944 | 1.00 | KAT6A (0.43) | KAT6AMGLLTAS1R3TAS1R1TAS1R2 | |
| SCHEMBL17134314 | 0.80 | NPC1 (0.49) | KAT6AMGLLTAS1R3TAS1R1TAS1R2 | |
| SCHEMBL7702314 | 0.80 | NPC1 (0.49) | KAT6AMGLLTAS1R3TAS1R1TAS1R2 | |
| SCHEMBL29478758 | 0.80 | KAT6A (0.46) | KAT6ATAS1R3TAS1R1TAS1R2F10 | |
| SCHEMBL1580873 | 0.80 | KAT6A (0.46) | KAT6ATAS1R3TAS1R1TAS1R2F10 | |
| SCHEMBL1580875 | 0.80 | KAT6A (0.46) | KAT6ATAS1R3TAS1R1TAS1R2F10 | |
| SCHEMBL29461392 | 0.79 | KAT6A (0.51) | KAT6AMGLLTAS1R3TAS1R1TAS1R2 | |
| SCHEMBL248669 | 0.79 | KAT6A (0.51) | KAT6AMGLLTAS1R3TAS1R1TAS1R2 | |
| SCHEMBL4040566 | 0.79 | GRIN2B (0.44) | GRIN2B | |
| SCHEMBL4040563 | 0.79 | GRIN2B (0.44) | GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2699566-B1 | PHENYL-ISOXAZOL DERIVATIVES AND PREPARATION PROCESS THEREOF | IL-YANG PHARM CO LTD (KR) | 2017-02-22 | — | — | EP | disclosed |
| US-9132126-B2 | Phenyl-isoxazole derivatives and preparation process thereof | IL-YANG PHARM. CO., LTD. (KR) | 2015-09-15 | — | — | US | disclosed |
| EP-2699566-A1 | PHENYL-ISOXAZOL DERIVATIVES AND PREPARATION PROCESS THEREOF | Il-Yang Pharm. Co., Ltd. (KR) | 2014-02-26 | — | — | EP | disclosed |
| US-20140031364-A1 | PHENYL-ISOXAZOL DERIVATIVES AND PREPARATION PROCESS THEREOF | IL-YANG PHARM. CO., LTD. (KR) | 2014-01-30 | — | — | US | disclosed |
| WO-2012144752-A1 | PHENYL-ISOXAZOL DERIVATIVES AND PREPARATION PROCESS THEREOF | IL-YANG PHARM. CO., LTD. (KR) | 2012-10-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140031364-A1 | PHENYL-ISOXAZOL DERIVATIVES AND PREPARATION PROCESS THEREOF | PIR, ALPL, PIGS | KAT6A 3101/4885MGLL 1570/4885TAS1R3 4384/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.