Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | PELP1 | Q8IZL8 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.40 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.40 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.40 |
| ▸ | GMNN | O75496 | 1/20 | 0.40 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.40 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31056786 | 0.76 | VCAM1 (0.50) | VCAM1HPGDALDH1A1MAPTRAB9A | |
| SCHEMBL1346767 | 0.72 | AR (0.61) | VCAM1HPGDALDH1A1MAPTPTGER4 | |
| SCHEMBL5734347 | 0.71 | VCAM1 (0.68) | VCAM1HPGDALDH1A1MAPTKMT2A | |
| SCHEMBL20266487 | 0.71 | ALDH1A1 (0.67) | VCAM1ALDH1A1MAPTPTGER4RAB9A | |
| SCHEMBL29560026 | 0.71 | ALDH1A1 (0.67) | VCAM1ALDH1A1MAPTPTGER4RAB9A | |
| SCHEMBL8169431 | 0.71 | AR (0.60) | VCAM1HPGDALDH1A1MAPTPTGER4 | |
| SCHEMBL2876988 | 0.70 | VCAM1 (0.55) | VCAM1HPGDALDH1A1ARPELP1 | |
| SCHEMBL4125942 | 0.70 | VCAM1 (0.55) | VCAM1HPGDALDH1A1MAPTAR | |
| SCHEMBL29995132 | 0.70 | VCAM1 (0.55) | VCAM1HPGDALDH1A1ARPELP1 | |
| SCHEMBL4285904 | 0.70 | VCAM1 (0.55) | VCAM1HPGDALDH1A1MAPTPTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009099087-A1 | BENZYLPIPERIZINE COMPOUND | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2009-08-13 | — | — | WO | disclosed |