Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | ERN1 | O75460 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | MYC | P01106 | 1/20 | 0.43 |
| ▸ | MAX | P61244 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.43 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14691018 | 0.90 | VCAM1 (0.53) | VCAM1HPGDMEN1KMT2AALDH1A1 | |
| SCHEMBL27783481 | 0.81 | MAPT (0.41) | VCAM1HPGDMEN1KMT2AALDH1A1 | |
| SCHEMBL3470896 | 0.80 | NPC1 (0.57) | VCAM1HPGDMEN1KMT2AALDH1A1 | |
| SCHEMBL20835506 | 0.79 | CA12 (0.56) | HPGDERN1MEN1KMT2AALDH1A1 | |
| SCHEMBL31056715 | 0.78 | NPC1 (0.47) | HPGDMEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL31056174 | 0.78 | KDM4E (0.50) | HPGDALDH1A1NPSR1PKMNPC1 | |
| SCHEMBL2476070 | 0.78 | NPC1 (0.47) | MEN1KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL5734347 | 0.77 | VCAM1 (0.68) | VCAM1HPGDERN1MEN1KMT2A | |
| SCHEMBL13734826 | 0.76 | VCAM1 (0.44) | VCAM1HPGDMEN1KMT2AALDH1A1 | |
| SCHEMBL19927553 | 0.76 | ALDH1A1 (0.45) | HPGDKMT2AALDH1A1PKMSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024178390-A1 | COVALENT MODIFIERS OF AKT1 AND USES THEREOF | TERREMOTO BIOSCIENCES, INC. (US) | 2024-08-29 | — | — | WO | disclosed |