Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A1 | P43005 | 2/20 | 0.54 |
| ▸ | GSR | P00390 | 2/20 | 0.54 |
| ▸ | GRM8 | O00222 | 2/20 | 0.54 |
| ▸ | GRM6 | O15303 | 2/20 | 0.54 |
| ▸ | GRM7 | Q14831 | 2/20 | 0.54 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.54 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.54 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.54 |
| ▸ | GRM5 | P41594 | 1/20 | 0.54 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.54 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.54 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.54 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.54 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.54 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.54 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.54 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.54 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5089980 | 0.86 | GRIK1 (0.52) | SLC1A1GSRGRM8GRM6GRM7 | |
| SCHEMBL435289 | 0.84 | SLC1A1 (0.34) | SLC1A1GSRGRM8GRM6GRM7 | |
| SCHEMBL5053704 | 0.82 | SLC1A1 (0.34) | SLC1A1GSRGRM8GRM6GRM7 | |
| SCHEMBL3734634 | 0.79 | BLM (0.32) | SLC1A1GSRGRM8GRM6GRM7 | |
| SCHEMBL3196025 | 0.79 | GRIK1 (0.48) | SLC1A1GRIK1GRIA1GRIA2GRIA4 | |
| SCHEMBL28196876 | 0.79 | GRIK1 (0.48) | SLC1A1GRIK1GRIA1GRIA2GRIA4 | |
| SCHEMBL10932186 | 0.79 | SLC1A1 (0.62) | SLC1A1GSRGRM8GRM6GRM7 | |
| SCHEMBL21777206 | 0.78 | GRM8 (0.31) | SLC1A1GSRGRM8GRM6GRM7 | |
| SCHEMBL25430984 | 0.77 | SLC1A1 (0.50) | SLC1A1GSRGRM8GRM6GRM7 | |
| SCHEMBL23303349 | 0.77 | SLC1A1 (0.50) | SLC1A1GSRGRM8GRM6GRM7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 94 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240124863-A1 | EVOLUTION OF PROTEASES | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2024-04-18 | — | — | US | disclosed |
| WO-2024050007-A1 | GTP CYCLOHYDROLASE-CLEAVING PROTEASES | THE BROAD INSTITUTE, INC. (US) | 2024-03-07 | — | — | WO | disclosed |
| US-11912664-B2 | Determining small molecule-protein and protein-protein interactions | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2024-02-27 | — | — | US | disclosed |
| WO-2024038447-A1 | CHIMERIC CASEIN AND WHEY PROTEINS AND USE THEREOF | IMAGINDAIRY LTD. (IL) | 2024-02-22 | — | — | WO | disclosed |
| US-20240052331-A1 | EVOLUTION OF BOTULINUM NEUROTOXIN PROTEASES | THE BOARD INSTITUTE, INC. (US) | 2024-02-15 | — | — | US | disclosed |
| WO-2024003418-A1 | IMPROVED DOWNREGULATION OF HISTONE CYTOTOXICITY BY COMPLEX OF NEGATIVELY CHARGED POLYSACCHARIDE AND PROTEASE | UNIVERSITEIT MAASTRICHT (NL) | 2024-01-04 | — | — | WO | disclosed |
| US-20230365624-A1 | NOVEL ANGIOTENSIN I-CONVERTING ENZYME (ACE) INHIBITORY PEPTIDES | THAI UNION GROUP PUBLIC CO LTD (TH) | 2023-11-16 | — | — | US | disclosed |
| CN-114045319-B | Control of restriction enzyme activity using proteases | 武汉爱博泰克生物科技有限公司 | 2023-10-17 | — | — | CN | disclosed |
| EP-4256070-A1 | NOVEL ANGIOTENSIN I-CONVERTING ENZYME (ACE) INHIBITORY PEPTIDES | Thai Union Group Public Company Limited (TH) | 2023-10-11 | — | — | EP | disclosed |
| US-11781126-B2 | Using proteases to control star activity of restriction enzymes | ABCLONAL SCIENCE, INC. (US) | 2023-10-10 | — | — | US | disclosed |
| WO-2015179402-A1 | METHODS OF FOLDING A GRAFT COPOLYMER WITH DUAL ANTICANCER DRUGS AND RELATED APPLICATIONS | NORTH CAROLINA STATE UNIVERSITY (US) | 2015-11-26 | — | — | WO | disclosed |
| US-20150290362-A1 | HYBRID FIBRIN-MICROGEL CONSTRUCTS FOR TISSUE REPAIR AND REGENERATION | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2015-10-15 | — | — | US | disclosed |
| US-20140079638-A1 | NOVEL CONJUGATES OF POLYMERS HAVING A THERAPEUTICALLY ACTIVE AGENT AND AN ANGIOGENESIS TARGETING MOIETY ATTACHED THERETO AND USES THEREOF IN THE TREATMENT OF ANGIOGENESIS RELATED DISEASES | Fundacion de la Comunidad Valenciana Centro de Investigacion Principle Felipe (ES) | 2014-03-20 | — | — | US | disclosed |
| US-8586019-B2 | Conjugates of polymers having a therapeutically active agent and an angiogenesis targeting moiety attached thereto and uses thereof in the treatment of angiogenesis related diseases | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2013-11-19 | — | — | US | disclosed |
| US-20110286923-A1 | NOVEL CONJUGATES OF POLYMERS HAVING A THERAPEUTICALLY ACTIVE AGENT AND AN ANGIOGENESIS TARGETING MOIETY ATTACHED THERETO AND USES THEREOF IN THE TREATMENT OF ANGIOGENESIS RELATED DISEASES | Fundacion de la Communidad Valenciana Centro de Investigacion principe felipe (ES) | 2011-11-24 | — | — | US | disclosed |
| CN-102105156-A | Novel conjugates of polymers having attached therapeutically active agents and angiogenesis targeting moieties and their use in treating angiogenesis-related diseases | UNIV RAMOT | 2011-06-22 | — | — | CN | disclosed |
| US-20110091577-A1 | DRUG RELEASE COATINGS ON CALCUIM PHOSPHATE AND USES THEREOF | ALBERT EINSTEIN COLLEGE OF MEDICINE, INC. | 2011-04-21 | — | — | US | disclosed |
| EP-2307032-A2 | NOVEL CONJUGATES OF POLYMERS HAVING A THERAPEUTICALLY ACTIVE AGENT AND AN ANGIOGENESIS TARGETING MOIETY ATTACHED THERETO AND USES THEREOF IN THE TREATMENT OF ANGIOGENESIS RELATED DISEASES | Ramot at Tel-Aviv University Ltd. (IL) | 2011-04-13 | — | — | EP | disclosed |
| WO-2009141826-A2 | NOVEL CONJUGATES OF POLYMERS HAVING A THERAPEUTICALLY ACTIVE AGENT AND AN ANGIOGENESIS TARGETING MOIETY ATTACHED THERETO AND USES THEREOF IN THE TREATMENT OF ANGIOGENESIS RELATED DISEASES | RAMOT AT TEL AVIV UNIVERSITY LTD. (IL) | 2009-11-26 | — | — | WO | disclosed |
| WO-2009131638-A2 | DRUG RELEASE COASTINGS ON CALCIUM PHOSPHATE AND USES THEREOF | YESHIVA UNIVERSITY (US) | 2009-10-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140079638-A1 | NOVEL CONJUGATES OF POLYMERS HAVING A THERAPEUTICALLY ACTIVE AGENT AND AN ANGIOGENESIS TARGETING MOIETY ATTACHED THERETO AND USES THEREOF IN THE TREATMENT OF ANGIOGENESIS RELATED DISEASES | VEGFA, FLT4, FLT1 | SLC1A1 3753/4885GSR 2462/4885GRM8 3577/4885 |
| US-20110286923-A1 | NOVEL CONJUGATES OF POLYMERS HAVING A THERAPEUTICALLY ACTIVE AGENT AND AN ANGIOGENESIS TARGETING MOIETY ATTACHED THERETO AND USES THEREOF IN THE TREATMENT OF ANGIOGENESIS RELATED DISEASES | VEGFA, FLT4, FLT1 | SLC1A1 3753/4885GSR 2462/4885GRM8 3577/4885 |
| US-11912664-B2 | Determining small molecule-protein and protein-protein interactions | MAX, IK, CRYAA | SLC1A1 2638/4885GSR 4628/4885GRM8 3099/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.