Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 14/20 | 0.48 |
| ▸ | GRIK2 | Q13002 | 9/20 | 0.48 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.48 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.48 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.41 |
| ▸ | GRIA4 | P48058 | 3/20 | 0.41 |
| ▸ | GRIK3 | Q13003 | 3/20 | 0.41 |
| ▸ | GRIK5 | Q16478 | 3/20 | 0.41 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.41 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.39 |
| ▸ | GGT1 | P19440 | 2/20 | 0.39 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3196025 | 1.00 | GRIK1 (0.48) | GRIK1GRIK2GRM1GRM2SLC7A5 | |
| SCHEMBL3788767 | 0.85 | GRIK1 (0.47) | GRIK1GRIK2GRM1GRM2SLC7A5 | |
| SCHEMBL9614483 | 0.83 | GRIK1 (0.30) | GRIK1GRIK2GRM1GRM2 | |
| SCHEMBL1373501 | 0.79 | SLC1A1 (0.54) | GRIK1GRIK2GRM1GRM2GRIA4 | |
| SCHEMBL4860820 | 0.78 | SLC1A1 (0.32) | SLC1A1 | |
| SCHEMBL28293178 | 0.76 | SMN1; SMN2 (0.48) | — | |
| SCHEMBL25428744 | 0.75 | GRIK1 (0.42) | GRIK1GRIK2GRM1GRM2SLC7A5 | |
| SCHEMBL14328763 | 0.75 | ARG1 (0.36) | GRIK1GRIK2GRM1GRM2SLC7A5 | |
| SCHEMBL14388352 | 0.75 | GRIK1 (0.48) | GRIK1GRIK2GRM1GRM2SLC7A5 | |
| SCHEMBL14882533 | 0.75 | GRIK1 (0.48) | GRIK1GRIK2GRM1GRM2SLC7A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105254573-B | A kind of preparation method of Taltirelin and its intermediate | 重庆莱美隆宇药业有限公司 | 2018-01-23 | — | — | CN | claimed |