SCHEMBL435289

SCHEMBL435289

N[C@@H](CCC(=O)OC=O)C(=O)OC=O

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC1A1 P43005 2/20 0.34
GRM8 O00222 1/20 0.34
GRM6 O15303 1/20 0.34
GRIN2D O15399 1/20 0.34
GRIN3B O60391 1/20 0.34
GSR P00390 1/20 0.34
CYP1A2 P05177 1/20 0.34
GRIK1 P39086 1/20 0.34
GRM5 P41594 1/20 0.34
GRIA1 P42261 1/20 0.34
GRIA2 P42262 1/20 0.34
GRIA3 P42263 1/20 0.34
SLC1A3 P43003 1/20 0.34
SLC1A2 P43004 1/20 0.34
GRIA4 P48058 1/20 0.34
GRIN1 Q05586 1/20 0.34
GRIN2A Q12879 1/20 0.34
GRIK2 Q13002 1/20 0.34
GRIK3 Q13003 1/20 0.34
GRIN2B Q13224 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3734634 0.91 BLM (0.32) SLC1A1GRM8GRM6GRIN2DGRIN3B
SCHEMBL21777206 0.85 GRM8 (0.31) SLC1A1GRM8GRM6GRIN2DGRIN3B
SCHEMBL5053704 0.85 SLC1A1 (0.34) SLC1A1GRM8GRM6GRIN2DGRIN3B
SCHEMBL1373501 0.84 SLC1A1 (0.54) SLC1A1GRM8GRM6GRIN2DGRIN3B
SCHEMBL15391928 0.84 ALOX15 (0.52) SLC1A1GRM8GRM6GRIN2DGRIN3B
SCHEMBL20570145 0.83 LTA4H (0.39) SLC1A1BLMKMT2ASLC6A2SLC6A4
SCHEMBL11655301 0.82 BLM (0.34) SLC1A1GRM8GRM6GRIN2DGRIN3B
SCHEMBL5089985 0.82 BLM (0.34) SLC1A1GRM8GRM6GRIN2DGRIN3B
SCHEMBL9614483 0.79 GRIK1 (0.30) GRIK1GRIK2GRM1GRM2
SCHEMBL9551098 0.79

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 442 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4297903-A1 APPARATUS FOR BIOMOLECULE ASSAY Seer, Inc. (US) 2024-01-03 EP claimed
EP-3827076-A1 IN VIVO DELIVERY SYSTEM OF THE GENOME DNA MODIFYING ENZYMES AND THE USE THEREOF Uniwersytet Jagiellonski (PL) 2021-06-02 EP claimed
WO-2020021312-A1 IN VIVO DELIVERY SYSTEM OF THE GENOME DNA MODIFYING ENZYMES AND THE USE THEREOF UNIWERSYTET JAGIELLONSKI (PL) 2020-01-30 WO claimed
EP-1406930-A2 ISOLATED MOLECULES COMPRISING EPITOPES CONTAINING SULFATED MOIETIES, ANTIBODIES TO SUCH EPITOPES, AND USES THEREOF BIO-TECHNOLOGY GENERAL CORPORATION (US) 2004-04-14 EP claimed
US-20040002450-A1 Y17 - isolated molecules comprising epitopes containing sulfated moieties, antibodies to such epitopes, and uses thereof BIO-TECHNOLOGY GENERAL (ISRAEL) LTD. (IL) 2004-01-01 US claimed
US-20040001822-A1 Y1-isolated molecules comprising epitopes containing sulfated moieties, antibodies to such epitopes, and uses thereof BIO-TECHNOLOGY GENERAL (ISRAEL) LTD. (IL) 2004-01-01 US claimed
US-20040001839-A1 Multimers - isolated molecules comprising epitopes containing sulfated moieties, antibodies to such epitopes, and uses thereof BIO-TECHNOLOGY GENERAL (ISRAEL) LTD. (IL) 2004-01-01 US claimed
WO-2002053700-A2 ISOLATED MOLECULES COMPRISING EPITOPES CONTAINING SULFATED MOIETIES, ANTIBODIES TO SUCH EPITOPES, AND USES THEREOF BIO-TECHNOLOGY GENERAL CORP. (US) 2002-07-11 WO claimed
EP-0959884-A4 1999-12-15 EP claimed
EP-0959884-A1 PHOSPHATASE INHIBITORS AND METHODS OF USE THEREOF UNIVERSITY OF PITTSBURGH (US) 1999-12-01 EP claimed
US-5856506-A (OXAZOLYLCARBONYLAMINO)ETHYLAMINO GLUTAMATE DERIVATIVES UNIVERSITY OF PITTSBURGH (US) 1999-01-05 US claimed
WO-1998004257-A1 PHOSPHATASE INHIBITORS AND METHODS OF USE THEREOF UNIVERSITY OF PITTSBURGH (US) 1998-02-05 WO claimed
US-4960881-A REACTING AMINO ACID WITH ALPHA-CHLORINATED CARBONATE IN SOLVENT IN PRESENCE OF ACID SCAVENGER SOCIETE NATIONALE DES POUDRES ET EXPLOSIFS (FR) 1990-10-02 US claimed
WO-2026090578-A1 CDH17-BINDING ANTIBODIES AND METHODS OF USE THEREOF Antharis Therapeutics Inc. (US) 2026-04-30 WO disclosed
EP-4731651-A1 DUAL TRANSPORTERS AND METHODS OF USE Denali Therapeutics Inc. (US) 2026-04-29 EP disclosed
EP-4724458-A2 PEPTIDE THERAPEUTICS The Regents of the University of California (US) 2026-04-15 EP disclosed
US-5633350-A Method for the isolation and purification of vitamin K-dependent proteins IMMUNO AKTIENGESELLSCHAFT (AT) 1997-05-27 US disclosed
EP-0683226-A1 Transgenic animals as a model for metabolic bone diseases HOECHST JAPAN KABUSHIKI KAISHA (JP) 1995-11-22 EP disclosed
WO-1994029242-A1 THE BIOREMEDIATION OF SOILS CONTAINING HYDROCARBON USING CALCIUM PEROXIDE FMC CORPORATION (US) 1994-12-22 WO disclosed
WO-1989005652-A1 PURE FACTOR IX PRODUCT AMERICAN NATIONAL RED CROSS (US) 1989-06-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040001822-A1 Y1-isolated molecules comprising epitopes containing sulfated moieties, antibodies to such epitopes, and uses thereof CD47, CD14, SELE SLC1A1 3678/4885GRM8 4109/4885GRM6 3332/4885
US-20040001839-A1 Multimers - isolated molecules comprising epitopes containing sulfated moieties, antibodies to such epitopes, and uses thereof CD44, SELE, CD47 SLC1A1 3182/4885GRM8 3734/4885GRM6 2902/4885
US-20040002450-A1 Y17 - isolated molecules comprising epitopes containing sulfated moieties, antibodies to such epitopes, and uses thereof CD47, CD14, SELP SLC1A1 4169/4885GRM8 3632/4885GRM6 3668/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.