Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR5A | P47898 | 9/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.30 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.30 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.30 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4727852 | 0.78 | KMT2A (0.35) | KDM4EMAPT | |
| SCHEMBL10756431 | 0.73 | KDM1A (0.33) | HTR5ATSHRALDH1A1IDO1 | |
| SCHEMBL7837863 | 0.70 | HTR5A (0.36) | HTR5ATSHRALDH1A1MAPTADRA2A | |
| SCHEMBL4905747 | 0.70 | DDB1 (0.40) | ALDH1A1MAPTPDE4APDE4BPDE4C | |
| SCHEMBL14880451 | 0.69 | BRD4 (0.41) | ALDH1A1KDM4ECYP2D6 | |
| SCHEMBL6501917 | 0.67 | — | — | |
| SCHEMBL22203156 | 0.66 | — | — | |
| SCHEMBL10064030 | 0.66 | ALDH1A1 (0.33) | HTR5ATSHRALDH1A1IDO1 | |
| SCHEMBL11392187 | 0.65 | — | — | |
| SCHEMBL12603369 | 0.65 | ADRA1A (0.55) | ALDH1A1IDO1ADRA2AADRA1AADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3246373-B1 | ORGANIC MOLECULES FOR USE AS EMITTERS | CYNORA GMBH (DE) | 2019-01-30 | — | — | EP | claimed |
| EP-3137574-B1 | ORGANIC MOLECULES FOR USE AS EMITTERS | CYNORA GMBH (DE) | 2018-04-04 | — | — | EP | claimed |
| EP-3246373-A1 | ORGANIC MOLECULES FOR USE AS EMITTERS | cynora GmbH (DE) | 2017-11-22 | — | — | EP | claimed |
| US-20170288149-A1 | ORGANIC MOLECULES FOR USE AS EMITTERS | CYNORA GMBH (DE) | 2017-10-05 | — | — | US | claimed |
| EP-3137574-A1 | ORGANIC MOLECULES FOR USE AS EMITTERS | cynora GmbH (DE) | 2017-03-08 | — | — | EP | claimed |
| WO-2016042070-A1 | ORGANIC MOLECULES FOR USE AS EMITTERS | CYNORA GMBH (DE) | 2016-03-24 | — | — | WO | claimed |
| CN-118159626-A | Method for hydrotreating aromatic nitrogen compounds | 托普索公司 | 2024-06-07 | — | — | CN | disclosed |
| WO-2023151359-A1 | TETRAHYDROCARBAZOLE DERIVATIVE AS WELL AS PREPARATION METHOD THEREFOR AND USE THEREOF | 深圳湾实验室 | 2023-08-17 | — | — | WO | disclosed |
| US-11572368-B2 | Inhibitors of histone deacetylase | THE GENERAL HOSPITAL CORPORATION (US) | 2023-02-07 | — | — | US | disclosed |
| CN-114560804-A | Tetrahydrocarbazole derivative and preparation method and application thereof | 深圳湾实验室 | 2022-05-31 | — | — | CN | disclosed |
| EP-3611173-B1 | ORGANIC LIGHT EMITTING ELEMENT AND COMPOSITION FOR ORGANIC MATERIAL LAYER IN ORGANIC LIGHT EMITTING ELEMENT | LT MATERIALS CO LTD (KR) | 2021-07-28 | — | — | EP | disclosed |
| WO-2021103060-A1 | HOLE TRANSPORT MATERIAL, PREPARATION METHOD THEREFOR, AND ORGANIC LIGHT EMITTING DEVICE | 武汉华星光电半导体显示技术有限公司 | 2021-06-03 | — | — | WO | disclosed |
| US-10662199-B2 | Inhibitors of histone deacetylase | THE BROAD INSTITUTE, INC. (US) | 2020-05-26 | — | — | US | disclosed |
| WO-2016042070-A1 | ORGANIC MOLECULES FOR USE AS EMITTERS | CYNORA GMBH (DE) | 2016-03-24 | — | — | WO | disclosed |
| WO-2014088352-A1 | ORGANIC ELECTROLUMINESCENT COMPOUNDS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME | ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) | 2014-06-12 | — | — | WO | disclosed |
| US-20140080802-A1 | Inhibitors of Histone Deacetylase | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2014-03-20 | — | — | US | disclosed |
| US-20140080800-A1 | Inhibitors of Histone Deacetylase | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2014-03-20 | — | — | US | disclosed |
| EP-2701699-A1 | INHIBITORS OF HISTONE DEACETYLASE | The Broad Institute, Inc. (US) | 2014-03-05 | — | — | EP | disclosed |
| EP-2626404-A1 | Method of removing sulfur from crude oil and diesel using ionizing radiation | King Abdulaziz City for Science & Technology (KACST) (SA) | 2013-08-14 | — | — | EP | disclosed |
| WO-2012149540-A1 | INHIBITORS OF HISTONE DEACETYLASE | THE BROAD INSTITUTE INC (US) | 2012-11-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140080800-A1 | Inhibitors of Histone Deacetylase | HDAC2, HDAC1, HDAC11 | HTR5A 1566/4885TSHR 3090/4885ALDH1A1 1005/4885 |
| US-10662199-B2 | Inhibitors of histone deacetylase | HDAC2, HDAC1, HDAC11 | HTR5A 1566/4885TSHR 3090/4885ALDH1A1 1005/4885 |
| US-11572368-B2 | Inhibitors of histone deacetylase | HDAC2, HDAC1, HDAC11 | HTR5A 1566/4885TSHR 3090/4885ALDH1A1 1005/4885 |
| US-20140080802-A1 | Inhibitors of Histone Deacetylase | HDAC2, HDAC1, HDAC11 | HTR5A 1566/4885TSHR 3090/4885ALDH1A1 1005/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.