Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL515788 | 1.00 | ALDH1A1 (0.34) | ALDH1A1ALOX5 | |
| SCHEMBL9449773 | 1.00 | ALDH1A1 (0.34) | ALDH1A1ALOX5 | |
| SCHEMBL516008 | 0.98 | ALDH1A1 (0.36) | ALDH1A1ALOX5 | |
| SCHEMBL13333805 | 0.93 | ALDH1A1 (0.36) | ALDH1A1ALOX5 | |
| SCHEMBL9140299 | 0.88 | — | — | |
| SCHEMBL2435959 | 0.79 | POLB (0.32) | — | |
| SCHEMBL17277743 | 0.78 | NEK2 (0.31) | — | |
| SCHEMBL3728133 | 0.78 | — | — | |
| SCHEMBL4409815 | 0.77 | ALDH1A1 (0.34) | ALDH1A1ALOX5 | |
| SCHEMBL11956609 | 0.76 | ALOX5 (0.30) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9708270-B2 | Substituted spiropiperidinyl compounds useful as GPR120 agonists | MERCK SHARP & DOHME CORP. (US) | 2017-07-18 | — | — | US | disclosed |
| US-9464075-B2 | Influenza A virus inhibition | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2016-10-11 | — | — | US | disclosed |
| US-9464075-B2 | Influenza A virus inhibition | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2016-10-11 | — | — | US | disclosed |
| US-9464075-B2 | Influenza A virus inhibition | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2016-10-11 | — | — | US | disclosed |
| US-9453005-B2 | Inhibition of influenza M2 proton channel | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2016-09-27 | — | — | US | disclosed |
| US-9453005-B2 | Inhibition of influenza M2 proton channel | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2016-09-27 | — | — | US | disclosed |
| US-9453005-B2 | Inhibition of influenza M2 proton channel | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2016-09-27 | — | — | US | disclosed |
| US-9403777-B2 | Inhibitors of the influenza A virus M2 proton channel | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2016-08-02 | — | — | US | disclosed |
| US-20150299090-A1 | SPIRO COMPOUNDS AND PHARMACEUTICAL USE THEREOF | JAPAN TOBACCO INC. (JP) | 2015-10-22 | — | — | US | disclosed |
| US-20150299090-A1 | SPIRO COMPOUNDS AND PHARMACEUTICAL USE THEREOF | JAPAN TOBACCO INC. (JP) | 2015-10-22 | — | — | US | disclosed |
| WO-2010033339-A1 | INHIBITION OF INFLUENZA M2 PROTON CHANNEL | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2010-03-25 | — | — | WO | disclosed |
| WO-2010033339-A1 | INHIBITION OF INFLUENZA M2 PROTON CHANNEL | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2010-03-25 | — | — | WO | disclosed |
| WO-2010033340-A1 | INFLUENZA A VIRUS INHIBITION | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2010-03-25 | — | — | WO | disclosed |
| US-20090170908-A1 | SPIRO COMPOUNDS AND PHARMACEUTICAL USE THEREOF | JAPAN TOBACCO INC. (JP) | 2009-07-02 | — | — | US | disclosed |
| US-20090170908-A1 | SPIRO COMPOUNDS AND PHARMACEUTICAL USE THEREOF | JAPAN TOBACCO INC. (JP) | 2009-07-02 | — | — | US | disclosed |
| US-20090170908-A1 | SPIRO COMPOUNDS AND PHARMACEUTICAL USE THEREOF | JAPAN TOBACCO INC. (JP) | 2009-07-02 | — | — | US | disclosed |
| US-20090082463-A1 | N-substituted phenylacetamide derivative and pharmaceutical composition containing the same | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2009-03-26 | — | — | US | disclosed |
| EP-1884510-A1 | N-SUBSTITUTED PHENYLACETAMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | Dainippon Sumitomo Pharma Co., Ltd. (JP) | 2008-02-06 | — | — | EP | disclosed |
| EP-0074693-B1 | PERFUME COMPOSITIONS AND PERFUMED ARTICLES CONTAINING SPIRO-UNDECANONES AND -UNDECENONES AS PERFUME BASE | NAARDEN INTERNATIONAL N.V. (NL) | 1986-01-08 | — | — | EP | disclosed |
| US-4448712-A | Perfume compositions and perfumed articles containing spiro-undecanones and -undecenones as perfume base | NAARDEN INTERNATIONAL N.V. (NL) | 1984-05-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090170908-A1 | SPIRO COMPOUNDS AND PHARMACEUTICAL USE THEREOF | REN, PKD1, PKD2 | ALDH1A1 268/4885ALOX5 2719/4885 |
| US-20150299090-A1 | SPIRO COMPOUNDS AND PHARMACEUTICAL USE THEREOF | REN, PKD1, PKD2 | ALDH1A1 268/4885ALOX5 2719/4885 |
| US-20090082463-A1 | N-substituted phenylacetamide derivative and pharmaceutical composition containing the same | HRH4, HRH2, CNR2 | ALDH1A1 321/4885ALOX5 358/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.