Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA5A | P35218 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | CES2 | O00748 | 2/20 | 0.42 |
| ▸ | CES1 | P23141 | 2/20 | 0.42 |
| ▸ | ERN1 | O75460 | 1/20 | 0.40 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | FUT7 | Q11130 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CA3 | P07451 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | SELL | P14151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31346697 | 0.91 | CA5A (0.50) | CA5ALMNACES2CES1KDM4E | |
| SCHEMBL15495189 | 0.91 | CA5A (0.50) | CA5ALMNACES2CES1KDM4E | |
| SCHEMBL18629792 | 0.85 | TTR (0.47) | CA5ALMNACES2CES1HDAC1 | |
| SCHEMBL18593254 | 0.85 | CA5A (0.45) | CA5ALMNACES2CES1ERN1 | |
| SCHEMBL823677 | 0.82 | CES2 (0.64) | CA5ALMNACES2CES1KIF11 | |
| SCHEMBL31346652 | 0.82 | LMNA (0.75) | CA5ALMNACA12ALDH1A1CA1 | |
| SCHEMBL12799726 | 0.82 | LMNA (0.75) | CA5ALMNACA12ALDH1A1CA1 | |
| SCHEMBL13125486 | 0.80 | HDAC1 (0.59) | CA5ALMNACES2CES1KIF11 | |
| Bromide SCHEMBL31124417 | 0.80 | CES2 (0.61) | CA5ALMNACES2CES1KIF11 | |
| SCHEMBL96069 | 0.79 | LMNA (0.59) | CA5ALMNAHDAC1KDM4EFUT7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 99 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9556469-B2 | Method for classifying the presence or absence of a microorganism in a biological medium | COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) | 2017-01-31 | — | — | US | claimed |
| EP-2723885-B1 | METHOD FOR CLASSIFYING THE PRESENCE OR ABSENCE OF A MICROORGANISM IN A BIOLOGICAL MEDIUM | COMMISSARIAT L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) | 2015-08-12 | — | — | EP | claimed |
| US-20140162301-A1 | Method for Classifying the Presence or Absence of a Microorganism in a Biological Medium | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2014-06-12 | — | — | US | claimed |
| EP-2723885-A2 | METHOD FOR CLASSIFYING THE PRESENCE OR ABSENCE OF A MICROORGANISM IN A BIOLOGICAL MEDIUM | Commissariat à l'Énergie Atomique et aux Énergies Alternatives (FR) | 2014-04-30 | — | — | EP | claimed |
| WO-2013001465-A2 | METHOD FOR CLASSIFYING THE PRESENCE OR ABSENCE OF A MICROORGANISM IN A BIOLOGICAL MEDIUM | COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) | 2013-01-03 | — | — | WO | claimed |
| US-12161624-B2 | Selective octahydro-cyclopenta[c]pyrrole negative modulators of NR2B | NOVARTIS AG (CH) | 2024-12-10 | — | — | US | disclosed |
| US-20240199576-A1 | NOVEL CYCLOPENTA[C]PYRROL NEGATIVE ALLOSTERIC MODULATORS OF NR2B | NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH, INC. | 2024-06-20 | — | — | US | disclosed |
| EP-4313042-A1 | NOVEL CYCLOPENTA[C]PYRROL NEGATIVE ALLOSTERIC MODULATORS OF NR2B | Novartis AG (CH) | 2024-02-07 | — | — | EP | disclosed |
| CN-117120053-A | Novel cyclopenta [ c ] pyrrole NR2B negative allosteric modulators | 诺华股份有限公司 | 2023-11-24 | — | — | CN | disclosed |
| US-20230012073-A1 | SELECTIVE OCTAHYDRO-CYCLOPENTA[C]PYRROLE NEGATIVE MODULATORS OF NR2B | CADENT THERAPEUTICS, INC. (US) | 2023-01-12 | — | — | US | disclosed |
| US-20230012073-A1 | SELECTIVE OCTAHYDRO-CYCLOPENTA[C]PYRROLE NEGATIVE MODULATORS OF NR2B | CADENT THERAPEUTICS, INC. (US) | 2023-01-12 | — | — | US | disclosed |
| WO-2022204337-A1 | NOVEL CYCLOPENTA[C]PYRROL NEGATIVE ALLOSTERIC MODULATORS OF NR2B | NOVARTIS AG (CH) | 2022-09-29 | — | — | WO | disclosed |
| US-5900502-A | Fluorination process | BNFL FLUOROCHEMICALS LIMITED (GB) | 1999-05-04 | — | — | US | disclosed |
| US-5610020-A | CLEAVING TO LABEL MOLECULAR SPEICES IN ANALYTES; VOLATILE FOR DETERMINATION IN GAS PGHASE | NORTHEASTERN UNIVERSITY (US) | 1997-03-11 | — | — | US | disclosed |
| US-5604104-A | BIOLOGICAL ANALYSIS USING A CLEAVABLE LABEL CAPABLE OF VOLATILIZATION AND DETECTION IN THE VAPOR PHASE; MEDICAL DIAGNOSIS; HUMAN GENOME PROJECT; GENETIC DISORDERS | NORTHEASTERN UNIVERSITY (US) | 1997-02-18 | — | — | US | disclosed |
| US-5602273-A | WHEN CLEAVED RELEASE STABLE ELECTROPHORIC KETONES VOLATILE ENOUGH FOR DETERMINATION IN GAS PHASE | NORTHEASTERN UNIVERSITY (US) | 1997-02-11 | — | — | US | disclosed |
| EP-0734363-A1 | FLUORINATION PROCESS | BNFL FLUOROCHEMICALS LTD. (GB) | 1996-10-02 | — | — | EP | disclosed |
| US-5516931-A | AROMATIC FLUORINATED KETONES FOR CHEMICAL LABELS | NORTHEASTERN UNIVERSITY (US) | 1996-05-14 | — | — | US | disclosed |
| WO-1995016649-A1 | FLUORINATION PROCESS | BNFL FLUOROCHEMICALS LTD. (GB) | 1995-06-22 | — | — | WO | disclosed |
| US-3933472-A | Substituted alkylaryl ketones and methods of use as herbicides | BUCKMAN LABORATORIES, INC. (US) | 1976-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240199576-A1 | NOVEL CYCLOPENTA[C]PYRROL NEGATIVE ALLOSTERIC MODULATORS OF NR2B | GRIN2C, GRIN2B, GRIN2A | CA5A 2413/4885LMNA 4799/4885CES2 3587/4885 |
| US-20230012073-A1 | SELECTIVE OCTAHYDRO-CYCLOPENTA[C]PYRROLE NEGATIVE MODULATORS OF NR2B | GRIN2A, GRIN2C, GRIN3A | CA5A 1736/4885LMNA 4453/4885CES2 2181/4885 |
| US-12161624-B2 | Selective octahydro-cyclopenta[c]pyrrole negative modulators of NR2B | GRIN2A, GRIN2C, GRIN3A | CA5A 1736/4885LMNA 4453/4885CES2 2181/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.