Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 1/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CSF1R | P07333 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8418329 | 0.98 | SLC6A9 (0.46) | SLC6A9CYP11B1CYP11B2KDM4ETP53 | |
| SCHEMBL3164773 | 0.86 | ALDH1A1 (0.57) | KDM4ETP53ALDH1A1SMN1; SMN2LMNA | |
| Hydrochloric Acid SCHEMBL23303687 | 0.85 | ALDH1A1 (0.56) | KDM4ETP53ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL29817963 | 0.85 | ALDH1A1 (0.51) | KDM4ETP53ALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL10164866 | 0.85 | KDM4E (0.55) | SLC6A9KDM4ETP53ALDH1A1HPGD | |
| SCHEMBL15117102 | 0.84 | SLC6A9 (0.57) | SLC6A9CYP11B1CYP11B2ALDH1A1MEN1 | |
| SCHEMBL18656449 | 0.83 | DRD2 (0.41) | SLC6A9CYP11B1CYP11B2KDM4ETP53 | |
| SCHEMBL29818036 | 0.81 | ALDH1A1 (0.45) | KDM4ETP53ALDH1A1GFERKMT2A | |
| SCHEMBL4451927 | 0.77 | NOTUM (0.47) | SLC6A9KDM4EALDH1A1TDP1MEN1 | |
| SCHEMBL5716060 | 0.75 | ALDH1A1 (0.56) | KDM4EALDH1A1TDP1MEN1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012152983-A1 | PHENYL- SULFONYL DERIVATIVES AS MEDIATORS OF TRPA1 RECEPTOR ACTIVITY FOR THE TREATMENT OF PAIN | ORION CORPORATION (FI) | 2012-11-15 | — | — | WO | disclosed |