Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | LGMN | Q99538 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | PIK3C3 | Q8NEB9 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13386162 | 0.90 | MAPT (0.44) | MEN1KMT2AMAPTALDH1A1HPGD | |
| Iodide SCHEMBL13386326 | 0.89 | MAPT (0.44) | MEN1KMT2AMAPTALDH1A1HPGD | |
| SCHEMBL13386254 | 0.85 | MAPT (0.41) | MEN1KMT2AMAPTALDH1A1HPGD | |
| SCHEMBL13386320 | 0.83 | LMNA (0.40) | MEN1KMT2AMAPTALDH1A1HPGD | |
| SCHEMBL13386392 | 0.83 | LGMN (0.44) | MEN1KMT2AMAPTALDH1A1HPGD | |
| SCHEMBL13386113 | 0.83 | MAPT (0.44) | MEN1KMT2AMAPTALDH1A1HPGD | |
| SCHEMBL2594059 | 0.82 | MEN1 (0.39) | MEN1KMT2AMAPTALDH1A1HPGD | |
| SCHEMBL16004713 | 0.82 | MAPT (0.39) | MEN1KMT2AMAPTALDH1A1HPGD | |
| SCHEMBL13386124 | 0.82 | MAPT (0.39) | MEN1KMT2AMAPTALDH1A1HPGD | |
| SCHEMBL13386157 | 0.81 | ALDH1A1 (0.38) | MEN1KMT2AMAPTALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2699241-A1 | ANTIVIRAL COMPOUNDS | Prosetta Antiviral Inc. (US) | 2014-02-26 | — | — | EP | disclosed |
| WO-2012145567-A1 | ANTIVIRAL COMPOUNDS | PROSETTA ANTIVIRAL INC. (US) | 2012-10-26 | — | — | WO | disclosed |