Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.31 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.30 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.30 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.30 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.30 |
| ▸ | ACACB | O00763 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13831022 | 1.00 | CD274 (0.31) | CD274GPR119MAP4K4MINK1TNIK | |
| SCHEMBL13737835 | 1.00 | CD274 (0.31) | CD274GPR119MAP4K4MINK1TNIK | |
| SCHEMBL13831038 | 0.97 | ACACB (0.31) | ACACB | |
| SCHEMBL16843260 | 0.91 | ACACB (0.30) | ACACB | |
| SCHEMBL13738781 | 0.91 | ACACB (0.30) | ACACB | |
| SCHEMBL13738780 | 0.91 | ACACB (0.30) | ACACB | |
| SCHEMBL16840399 | 0.91 | ACACB (0.30) | ACACB | |
| SCHEMBL13740661 | 0.91 | ACACB (0.30) | ACACB | |
| SCHEMBL19102807 | 0.89 | GABRB1 (0.31) | — | |
| SCHEMBL18100458 | 0.89 | GABRB1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2638006-A1 | HYDROXAMIC ACID DERIVATIVES AND THEIR USE IN THE TREATMENT OF BACTERIAL INFECTIONS | Achaogen, Inc. (US) | 2013-09-18 | — | — | EP | disclosed |
| WO-2012154204-A1 | HYDROXAMIC ACID DERIVATIVES AND THEIR USE IN THE TREATMENT OF BACTERIAL INFECTIONS | ACHAOGEN, INC. (US) | 2012-11-15 | — | — | WO | disclosed |