Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRB1 | P18505 | 1/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19102807 | 1.00 | GABRB1 (0.31) | GABRB1GABRB2 | |
| SCHEMBL17435522 | 1.00 | GABRB1 (0.31) | GABRB1GABRB2 | |
| SCHEMBL17451859 | 1.00 | GABRB1 (0.31) | GABRB1GABRB2 | |
| SCHEMBL17451858 | 0.94 | GABRB1 (0.30) | GABRB1GABRB2 | |
| SCHEMBL17453177 | 0.94 | GABRB1 (0.30) | GABRB1GABRB2 | |
| SCHEMBL13831038 | 0.92 | ACACB (0.31) | — | |
| SCHEMBL13737835 | 0.89 | CD274 (0.31) | — | |
| SCHEMBL13737833 | 0.89 | CD274 (0.31) | — | |
| SCHEMBL13831022 | 0.89 | CD274 (0.31) | — | |
| SCHEMBL19102805 | 0.86 | PIN1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9701622-B2 | Antibacterial agents | ACHAOGEN, INC. (US) | 2017-07-11 | — | — | US | disclosed |
| US-20160280639-A1 | ANTIBACTERIAL AGENTS | ACHAOGEN, INC. | 2016-09-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160280639-A1 | ANTIBACTERIAL AGENTS | MRPL21, ABCB11, LSS | GABRB1 2495/4885GABRB2 2769/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.