Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRB1 | P18505 | 1/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18100458 | 1.00 | GABRB1 (0.31) | GABRB1GABRB2 | |
| SCHEMBL17435522 | 1.00 | GABRB1 (0.31) | GABRB1GABRB2 | |
| SCHEMBL17451859 | 1.00 | GABRB1 (0.31) | GABRB1GABRB2 | |
| SCHEMBL17451858 | 0.94 | GABRB1 (0.30) | GABRB1GABRB2 | |
| SCHEMBL17453177 | 0.94 | GABRB1 (0.30) | GABRB1GABRB2 | |
| SCHEMBL13831038 | 0.92 | ACACB (0.31) | — | |
| SCHEMBL13737835 | 0.89 | CD274 (0.31) | — | |
| SCHEMBL13737833 | 0.89 | CD274 (0.31) | — | |
| SCHEMBL13831022 | 0.89 | CD274 (0.31) | — | |
| SCHEMBL19102805 | 0.86 | PIN1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9701622-B2 | Antibacterial agents | ACHAOGEN, INC. (US) | 2017-07-11 | — | — | US | disclosed |