SCHEMBL13740281

SCHEMBL13740281

CCCCCCCCCCCCCCCCCCCCCCCCC(C(=O)O)[C@@H](CCCCCCCCCOC(=O)C(C)(C)C)O[Si](C)(C)C(C)(C)C

nearest known ligand 0.40

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 3/20 0.33
NAAA Q02083 1/20 0.33
FFAR1 O14842 1/20 0.33
HCAR2 Q8TDS4 1/20 0.33
MAPT P10636 1/20 0.33
LCK P06239 1/20 0.33
PPARD Q03181 1/20 0.33
ZDHHC20 Q5W0Z9 1/20 0.33
ZDHHC2 Q9UIJ5 1/20 0.33
GRIK1 P39086 1/20 0.32
GRIK2 Q13002 1/20 0.32
EPHX1 P07099 1/20 0.32
PRKCA P17252 2/20 0.32
TSHR P16473 2/20 0.31
ACE2 Q9BYF1 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13740280 1.00 GPR84 (0.33) GPR84NAAAFFAR1HCAR2MAPT
SCHEMBL15664622 0.90 ZDHHC7 (0.38) NAAAEPHX1PRKCATSHR
SCHEMBL15664623 0.90 ZDHHC7 (0.38) NAAAEPHX1PRKCATSHR
SCHEMBL8896939 0.82 FFAR1 (0.40) FFAR1MAPTPPARD
SCHEMBL8896932 0.82 FFAR1 (0.40) FFAR1MAPTPPARD
SCHEMBL1978036 0.80 FAAH (0.38) PRKCA
SCHEMBL13737820 0.80
SCHEMBL13737824 0.80
SCHEMBL9457346 0.79 GPR84 (0.42) GPR84FFAR1MAPTLCKPPARD
SCHEMBL657947 0.79 ALOX5 (0.44) GPR84FFAR1MAPTLCKPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2705367-A1 METHOD FOR DETERMINING THE PRESENCE OR ABSENCE OF A BIOMARKER Bangor University (GB) 2014-03-12 EP disclosed
WO-2012153111-A1 METHOD FOR DETERMINING THE PRESENCE OR ABSENCE OF A BIOMARKER BANGOR UNIVERSITY (GB) 2012-11-15 WO disclosed