Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | XBP1 | P17861 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.35 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | S100A4 | P26447 | 1/20 | 0.31 |
| ▸ | MTOR | P42345 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8510450 | 0.87 | ALDH1A1 (0.52) | ALDH1A1MAPTNPC1TP53MAPK1 | |
| SCHEMBL10860893 | 0.82 | ALDH1A1 (0.73) | ALDH1A1MAPTNPC1TP53MAPK1 | |
| SCHEMBL6774488 | 0.78 | TLR9 (0.34) | ALDH1A1MAPTNPC1TP53MAPK1 | |
| SCHEMBL27450647 | 0.75 | TSHR (0.52) | ALDH1A1MAPTHSD17B10LMNATSHR | |
| (Ethenylsulfonyl)Benzene SCHEMBL45672 | 0.75 | TLR9 (0.58) | ALDH1A1MAPTNPC1TP53MAPK1 | |
| (Ethenylsulfonyl)Benzene SCHEMBL1332952 | 0.75 | TLR9 (0.58) | ALDH1A1MAPTNPC1TP53MAPK1 | |
| (Ethenylsulfonyl)Benzene SCHEMBL1331367 | 0.75 | TLR9 (0.58) | ALDH1A1MAPTNPC1TP53MAPK1 | |
| SCHEMBL4698110 | 0.74 | TSHR (0.42) | ALDH1A1MAPTNPC1TP53MAPK1 | |
| SCHEMBL15653727 | 0.73 | NPC1 (0.41) | ALDH1A1MAPTNPC1TP53MAPK1 | |
| SCHEMBL50583 | 0.72 | TSHR (0.55) | ALDH1A1MAPTHSD17B10LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 258 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240140933-A1 | OXOINDOLINE COMPOUND FOR THE TREATMENT OF INFLAMMATORY DISEASES OR CANCER | HOFFMANN-LA ROCHE INC. (US) | 2024-05-02 | — | — | US | claimed |
| EP-4341252-A1 | OXOINDOLINE COMPOUND FOR THE TREATMENT OF INFLAMMATORY DISEASES OR CANCER | F. Hoffmann-La Roche AG (CH) | 2024-03-27 | — | — | EP | claimed |
| EP-1397438-B1 | DYE MIXTURES OF FIBER-REACTIVE AZODYES AND THE USE THEREOF | DYSTAR TEXTILFARBEN GMBH & CO (DE) | 2008-09-10 | — | — | EP | claimed |
| US-7060114-B2 | Dye mixtures of fiber-reactive azo dyes and the use thereof | DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) | 2006-06-13 | — | — | US | claimed |
| EP-1397439-B1 | DYE MIXTURES OF FIBER-REACTIVE AZODYES AND USE THEREOF | DYSTAR TEXTILFARBEN GMBH & CO (DE) | 2005-11-16 | — | — | EP | claimed |
| US-6962611-B2 | Dye mixtures of fiber-reactive azodyes and use thereof | DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) | 2005-11-08 | — | — | US | claimed |
| US-6946006-B2 | Black dye mixtures of fiber-reactive AZO dyes and use thereof for dyeing material containing hydroxy- and/or carboxamido groups | DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) | 2005-09-20 | — | — | US | claimed |
| CN-1178993-C | Orange and deep red mixture of reactive dyes | 德意志戴斯达纺织品及染料两合公司 | 2004-12-08 | — | — | CN | claimed |
| US-20040148714-A1 | Dye mixtures of fiber-reactive azodyes and the use thereof | DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) | 2004-08-05 | — | — | US | claimed |
| US-20040139567-A1 | Dye mixtures of fiber-reactive azodyes and use thereof | DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) | 2004-07-22 | — | — | US | claimed |
| US-5817779-A | Azo reactive dyes, their preparation and use | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 1998-10-06 | — | — | US | claimed |
| CN-1163291-A | Active dye, their preparation and use | CIBA GEIGY AG (CH) | 1997-10-29 | — | — | CN | claimed |
| EP-0785237-A1 | Reactive dyes, their preparation and use | Ciba SC Holding AG (CH) | 1997-07-23 | — | — | EP | claimed |
| US-5445654-A | Black dye mixtures of fiber-reactive azo dyes and use thereof for dyeing hydroxy- and/or carboxamido-containing fiber material | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-08-29 | — | — | US | claimed |
| CN-1099052-A | The black dye mixer of fiber-reactive azo dyes and application thereof | HOECHST AG (DE) | 1995-02-22 | — | — | CN | claimed |
| EP-0600322-A2 | Black mixtures of reactive azo dyes and their use in dyeing fibrous materials containing hydroxy and/or carbonamide groups | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-06-08 | — | — | EP | claimed |
| EP-0202570-B1 | REACTIVE DYES | BASF Aktiengesellschaft (DE) | 1989-03-22 | — | — | EP | claimed |
| US-4798887-A | Azo dyes of methylaniline disulfonic acid coupled with naphthylamine sulfonic acid | BASF AKTIENGESELLSCHAFT (DE) | 1989-01-17 | — | — | US | claimed |
| EP-0133283-B1 | WATER-SOLUBLE DISAZO COMPOUNDS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS DYESTUFFS | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-04-01 | — | — | EP | claimed |
| EP-0202570-A1 | Reactive dyes | BASF Aktiengesellschaft (DE) | 1986-11-26 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240140933-A1 | OXOINDOLINE COMPOUND FOR THE TREATMENT OF INFLAMMATORY DISEASES OR CANCER | IL1B, IL1A, IL1R1 | ALDH1A1 302/4885MAPT 3322/4885NPC1 131/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.