Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4A | O75164 | 1/20 | 0.37 |
| ▸ | KDM4B | O94953 | 1/20 | 0.37 |
| ▸ | KDM5C | P41229 | 1/20 | 0.37 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.37 |
| ▸ | MMP12 | P39900 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | TDO2 | P48775 | 1/20 | 0.32 |
| ▸ | AXL | P30530 | 1/20 | 0.31 |
| ▸ | PRKCI | P41743 | 1/20 | 0.31 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.30 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1056425 | 0.74 | KDM4A (0.37) | KDM4AKDM4BKDM5CKDM5BMMP12 | |
| SCHEMBL1747899 | 0.74 | KDM4A (0.37) | KDM4AKDM4BKDM5CKDM5BMMP12 | |
| SCHEMBL27497303 | 0.74 | KDM4A (0.37) | KDM4AKDM4BKDM5CKDM5BMMP12 | |
| SCHEMBL1021282 | 0.68 | MAPT (0.39) | MMP12MAPT | |
| SCHEMBL15224220 | 0.66 | KDM4A (0.41) | KDM4AKDM4BKDM5CKDM5B | |
| SCHEMBL28391879 | 0.65 | ALDH1A1 (0.34) | MMP12MAPT | |
| SCHEMBL28888432 | 0.65 | MMP12 (0.45) | MMP12MAPTCDK5CDK5R1 | |
| SCHEMBL27513844 | 0.64 | MEN1 (0.33) | AXLPRKCI | |
| SCHEMBL5375138 | 0.64 | — | — | |
| SCHEMBL21121896 | 0.62 | DYRK1A (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 214 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120025337-A | Preparation method of baroretinib | 合肥菁科生物科技有限公司 | 2025-05-23 | — | — | CN | claimed |
| CN-120004900-A | Albumetate preparation method of nylon | 南通常佑药业科技有限公司 | 2025-05-16 | — | — | CN | claimed |
| CN-119827675-A | Separation detection method of formamidine in pontine starting material | 重庆药友制药有限责任公司 | 2025-04-15 | — | — | CN | claimed |
| CN-118598877-A | Ola maleate preparation method of tenib | 艾美科健（中国）生物医药有限公司 | 2024-09-06 | — | — | CN | claimed |
| CN-118290348-A | Synthesis method of 4-chloropyrrolo pyrimidine compound or derivative thereof | 诚达药业股份有限公司 | 2024-07-05 | — | — | CN | claimed |
| CN-118191196-A | Method for measuring related substances of 4-chloropyrrolopyrimidine by gas chromatography | 湖北丽益医药科技有限公司 | 2024-06-14 | — | — | CN | claimed |
| CN-117720543-A | Preparation method of barytinib | 东北林业大学 | 2024-03-19 | — | — | CN | claimed |
| CN-117517528-A | Detection method of related substances in intermediate of ponatinib | 安徽迪合永欣药业有限公司 | 2024-02-06 | — | — | CN | claimed |
| CN-117486889-A | Preparation method of 4-chloropyrrolopyrimidine | 南京法恩化学有限公司 | 2024-02-02 | — | — | CN | claimed |
| CN-116375623-A | Novel synthesis method of baratinib and intermediate thereof | 浙江乐普药业股份有限公司 | 2023-07-04 | — | — | CN | claimed |
| CN-109422748-B | Method for synthesizing TNNI3K inhibitor | 南京理工大学 | 2021-06-22 | — | — | CN | claimed |
| CN-112898306-A | Preparation method of barretinib | 山东四环药业股份有限公司 | 2021-06-04 | — | — | CN | claimed |
| CN-112573978-A | High-efficiency halogenation synthesis method of aryl halide | 北京大学 | 2021-03-30 | — | — | CN | claimed |
| CN-111454261-A | Synthesis method of 4-chloro-pyrrolopyrimidine compound | 南京普锐达医药科技有限公司 | 2020-07-28 | — | — | CN | claimed |
| CN-108586465-B | Preparation method of barretinib | 江苏中邦制药有限公司 | 2020-06-02 | — | — | CN | claimed |
| CN-110790768-A | Production system of medical intermediate 4-chloro-pyrrolopyrimidine | 廖文杰 | 2020-02-14 | — | — | CN | claimed |
| CN-110724145-A | Synthetic method of medical intermediate 4-chloropyrrolopyrimidine | 廖文杰 | 2020-01-24 | — | — | CN | claimed |
| CN-109824675-A | A kind of synthetic method of 4- chloropyrrolo [2,3-d | 唐山师范学院 | 2019-05-31 | — | — | CN | claimed |
| CN-105884781-B | Preparation method of tofacitinib citrate | 山东罗欣药业集团股份有限公司 | 2018-04-20 | — | — | CN | claimed |
| CN-105884781-A | Preparation method of tofacitinib citrate | 山东罗欣药业集团股份有限公司 | 2016-08-24 | — | — | CN | claimed |