Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 1/20 | 0.34 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.31 |
| ▸ | POLA1 | P09884 | 1/20 | 0.31 |
| ▸ | POLG | P54098 | 1/20 | 0.31 |
| ▸ | FAP | Q12884 | 1/20 | 0.31 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13714795 | 0.85 | NT5E (0.33) | NT5EABCB11POLA1POLGFAP | |
| SCHEMBL13743181 | 0.78 | FDPS (0.39) | NT5EABCB11POLA1POLGFAP | |
| SCHEMBL13714779 | 0.76 | HPRT1 (0.43) | NT5ESLC22A6 | |
| SCHEMBL3854698 | 0.74 | HPRT1 (0.40) | NT5ESLC22A6 | |
| SCHEMBL13714841 | 0.74 | HSP90AA1 (0.33) | NT5E | |
| SCHEMBL3863287 | 0.72 | HPRT1 (0.37) | NT5ESLC22A6 | |
| SCHEMBL14621498 | 0.71 | SLC22A6 (0.46) | ABCB11POLA1POLGFAPSLC22A6 | |
| SCHEMBL13742912 | 0.70 | HPRT1 (0.44) | NT5ESLC22A6 | |
| SCHEMBL3853182 | 0.67 | HPRT1 (0.44) | NT5ESLC22A6 | |
| SCHEMBL13714781 | 0.67 | HPRT1 (0.44) | NT5ESLC22A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7579332-B2 | Nucleobase phosphonate analogs for antiviral treatment | GILEAD SCIENCES, INC. (US) | 2009-08-25 | — | — | US | disclosed |