SCHEMBL13743371

SCHEMBL13743371

CCCCCCOc1ccc(NC(=O)C2=C(O)C(Cc3ccccc3)NC2=O)cc1

nearest known ligand 0.51

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
FAAH O00519 18/20 0.51
NAMPT P43490 1/20 0.45
NR0B1 P51843 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13752567 0.91 MGAT2 (0.44) FAAH
SCHEMBL13743690 0.91 SERPINE1 (0.42) FAAH
SCHEMBL13743667 0.91 FAAH (0.52) FAAH
SCHEMBL13743359 0.84 GAA (0.46) FAAH
SCHEMBL13743926 0.82 NR0B1 (0.48) NR0B1
SCHEMBL13743244 0.81 FAAH (0.42) FAAHNAMPT
SCHEMBL13743754 0.80 NR0B1 (0.52) NR0B1
SCHEMBL13743929 0.77 NR0B1 (0.48) NR0B1
SCHEMBL13743203 0.77 NPC1 (0.50) NR0B1
SCHEMBL13743187 0.76 NR0B1 (0.47) NR0B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090203694-A1 INHIBITORS OF UNDECAPRENYL PYROPHOSPHATE SYNTHASE HURLEY TIMOTHY BRIAN 2009-08-13 US disclosed
US-20090203694-A1 INHIBITORS OF UNDECAPRENYL PYROPHOSPHATE SYNTHASE HURLEY TIMOTHY BRIAN 2009-08-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090203694-A1 INHIBITORS OF UNDECAPRENYL PYROPHOSPHATE SYNTHASE FDPS, UMPS, GGPS1 FAAH 2000/4885NAMPT 68/4885NR0B1 2001/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.