Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | SCN4A | P35499 | 2/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.36 |
| ▸ | GSR | P00390 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27906584 | 1.00 | SLC6A4 (0.39) | SLC6A4MTNR1AMTNR1BLMNAALDH1A1 | |
| SCHEMBL7197530 | 0.89 | SLC6A4 (0.37) | SLC6A4LMNAALDH1A1RECQLSCN4A | |
| SCHEMBL13743579 | 0.83 | SLC6A4 (0.44) | SLC6A4SCN4A | |
| SCHEMBL11406412 | 0.83 | SLC6A4 (0.44) | SLC6A4SCN4A | |
| SCHEMBL502622 | 0.82 | LMNA (0.40) | SLC6A4LMNAALDH1A1TRPA1GSR | |
| E968 SCHEMBL8463462 | 0.81 | ACP3 (0.39) | ALDH1A1 | |
| SCHEMBL13743580 | 0.80 | SCN4A (0.41) | SLC6A4LMNAALDH1A1RECQLSCN4A | |
| SCHEMBL10338422 | 0.80 | THRB (0.46) | SLC6A4LMNAALDH1A1TRPA1GSR | |
| SCHEMBL13743855 | 0.79 | TRPA1 (0.44) | SLC6A4MTNR1AMTNR1BLMNAALDH1A1 | |
| SCHEMBL5307465 | 0.79 | SLC6A4 (0.49) | SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090198080-A1 | METHOD FOR THE PREPARATION OF ARYL ETHERS | PFIZER INC | 2009-08-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090198080-A1 | METHOD FOR THE PREPARATION OF ARYL ETHERS | CYP2E1, CBR1, CYP1A1 | SLC6A4 2765/4885MTNR1A 170/4885MTNR1B 154/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.