Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.54 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.53 |
| ▸ | ABCB1 | P08183 | 5/20 | 0.51 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.50 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29409810 | 0.87 | ALOX5 (0.55) | MAOBALOX5ABCB1HTR1ADRD2 | |
| SCHEMBL4077230 | 0.84 | MTNR1A (0.47) | MAOBALOX5ABCB1HTR1APDGFRB | |
| SCHEMBL27489226 | 0.83 | MAOB (0.53) | MAOBALOX5ABCB1HTR1ADRD2 | |
| SCHEMBL28108815 | 0.81 | MAOB (0.59) | MAOBABCB1HTR1ADRD2HDAC8 | |
| SCHEMBL7345409 | 0.80 | MAOB (0.51) | MAOBALOX5ABCB1HTR1ADRD2 | |
| SCHEMBL7827220 | 0.79 | PDGFRB (0.59) | MAOBALOX5ABCB1HTR1ADRD2 | |
| SCHEMBL19267891 | 0.79 | ABCB1 (0.58) | MAOBABCB1HTR1ADRD2PPARG | |
| SCHEMBL21957670 | 0.77 | MAOB (0.54) | MAOBABCB1HTR1ADRD2HDAC8 | |
| SCHEMBL23906959 | 0.77 | MAOB (0.79) | MAOBALOX5ABCB1MAPTMAPK1 | |
| SCHEMBL21582171 | 0.77 | ALOX5 (0.56) | MAOBALOX5PDGFRBPDGFRAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090215908-A1 | TOLL LIKE RECEPTOR (TLR) SIGNALING ANTAGONIST | RELIANCE LIFE SCIENCES PVT. LTD. (IN) | 2009-08-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090215908-A1 | TOLL LIKE RECEPTOR (TLR) SIGNALING ANTAGONIST | TLR4, TLR5, TLR1 | MAOB 3382/4885ALOX5 275/4885ABCB1 3233/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.