Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1A | P07327 | 5/20 | 0.37 |
| ▸ | ADH1C | P00326 | 3/20 | 0.37 |
| ▸ | ADH4 | P08319 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | PHGDH | O43175 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17322471 | 0.97 | ADH1A (0.41) | ADH1AADH1CADH4FAAHPHGDH | |
| SCHEMBL20938715 | 0.97 | ADH1C (0.33) | ADH1AADH1CADH4FAAHPHGDH | |
| SCHEMBL20662420 | 0.95 | ADH1A (0.39) | ADH1AADH1CADH4FAAHPHGDH | |
| SCHEMBL14199759 | 0.91 | JAK1 (0.31) | — | |
| SCHEMBL1678875 | 0.88 | ADH1A (0.43) | ADH1AADH1CADH4FAAHPHGDH | |
| SCHEMBL1356265 | 0.85 | ADH1A (0.48) | ADH1AADH1CADH4FAAHPHGDH | |
| SCHEMBL1679036 | 0.85 | ADH1A (0.48) | ADH1AADH1CADH4FAAHPHGDH | |
| SCHEMBL1678463 | 0.85 | ADH1A (0.48) | ADH1AADH1CADH4FAAHPHGDH | |
| SCHEMBL22837457 | 0.85 | ADH1A (0.46) | ADH1AADH1CADH4FAAHPHGDH | |
| SCHEMBL411186 | 0.85 | ADH1A (0.46) | ADH1AADH1CADH4FAAHPHGDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090209511-A1 | Benzofuran Derivatives | KAWAGUCHI TAKAYUKI | 2009-08-20 | — | — | US | disclosed |
| US-20090209511-A1 | Benzofuran Derivatives | KAWAGUCHI TAKAYUKI | 2009-08-20 | — | — | US | disclosed |
| US-7384952-B2 | Pyrazolopyrimidine compound and a process for preparing the same | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2008-06-10 | — | — | US | disclosed |
| US-7384952-B2 | Pyrazolopyrimidine compound and a process for preparing the same | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2008-06-10 | — | — | US | disclosed |
| EP-1857459-A2 | Pyrazolopyrimidine compound and a process for preparing the same | TANABE SEIYAKU CO., LTD. (JP) | 2007-11-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090209511-A1 | Benzofuran Derivatives | F12, F2, F3 | ADH1A 497/4885ADH1C 1019/4885ADH4 2063/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.