SCHEMBL13744955

SCHEMBL13744955

CC(C)[C@H]1C(=O)N(Cc2cccc(Br)c2)C[C@H]2N1C(=O)N(C)N2C(=O)NCc1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ CLPP Q16740 19/20 0.44
▸ CACNA1G O43497 1/20 0.37
▸ CACNA1H O95180 1/20 0.37
▸ CACNA1I Q9P0X4 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL746325 0.88 CLPP (0.46) CLPP
SCHEMBL743663 0.83 CLPP (0.43) CLPP
SCHEMBL13745014 0.83 CLPP (0.53) CLPP
SCHEMBL750277 0.82 CLPP (0.45) CLPP
SCHEMBL744855 0.81 CLPP (0.56) CLPP
SCHEMBL13184740 0.80 CLPP (0.56) CLPP
SCHEMBL13369113 0.79 CLPP (0.47) CLPP
SCHEMBL400299 0.79 CACNA1I (0.49) CACNA1GCACNA1HCACNA1I
SCHEMBL747659 0.79 CLPP (0.55) CLPP
SCHEMBL747317 0.79 CLPP (0.49) CLPPCACNA1GCACNA1HCACNA1I

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090215783-A1 COMPOSITION FOR INDUCTION OR INHIBITION OF STEM CELL DIFFERENTIATION CHOONGWAE PHARMA CORPORATION (KR) 2009-08-27 — — US disclosed
US-20090215783-A1 COMPOSITION FOR INDUCTION OR INHIBITION OF STEM CELL DIFFERENTIATION CHOONGWAE PHARMA CORPORATION (KR) 2009-08-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090215783-A1 COMPOSITION FOR INDUCTION OR INHIBITION OF STEM CELL DIFFERENTIATION MYLK2, TNNC1, MYH2 CLPP 3986/4885CACNA1G 2927/4885CACNA1H 2992/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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