Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | HPGD | P15428 | 3/20 | 0.62 |
| ▸ | USP2 | O75604 | 1/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13745507 | 0.90 | MAPT (0.62) | CYP3A4KDM4EALDH1A1HPGDUSP2 | |
| SCHEMBL13745660 | 0.86 | TSHR (0.72) | CYP3A4KDM4EALDH1A1GAATSHR | |
| SCHEMBL13627855 | 0.85 | CYP3A4 (0.67) | CYP3A4KDM4EALDH1A1HPGDUSP2 | |
| SCHEMBL24334503 | 0.85 | MAPT (0.53) | CYP3A4KDM4EALDH1A1HPGDUSP2 | |
| SCHEMBL24334510 | 0.85 | MAPT (0.53) | CYP3A4KDM4EALDH1A1HPGDUSP2 | |
| SCHEMBL3436777 | 0.82 | GNAI3 (0.50) | CYP3A4KDM4EALDH1A1USP2HSD17B10 | |
| SCHEMBL13745305 | 0.82 | GAA (0.62) | CYP3A4KDM4EALDH1A1GAATSHR | |
| SCHEMBL22652025 | 0.82 | NAAA (0.63) | CYP3A4KDM4EALDH1A1HPGDUSP2 | |
| SCHEMBL24098152 | 0.81 | GNAI3 (0.68) | CYP3A4KDM4EALDH1A1GAATSHR | |
| SCHEMBL15624788 | 0.81 | GNAI3 (0.59) | CYP3A4KDM4EALDH1A1HPGDUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022078350-A1 | METHODS AND COMPOSITIONS FOR TARGETED PROTEIN DEGRADATION | RANOK THERAPEUTICS (HANGZHOU) CO. LTD. (CN) | 2022-04-21 | — | — | WO | disclosed |
| WO-2009098282-A1 | LOW MOLECULAR WEIGHT 2,5-DISUBSTITUTED THIOPHENE DERIVATIVES AND USE THEREOF IN THERAPY | NOVASAID AB (SE) | 2009-08-13 | — | — | WO | disclosed |