Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.70 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.67 |
| ▸ | GAA | P10253 | 1/20 | 0.66 |
| ▸ | POLB | P06746 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 1/20 | 0.65 |
| ▸ | TSHR | P16473 | 2/20 | 0.64 |
| ▸ | PKM | P14618 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | GLA | P06280 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15453396 | 0.89 | ALDH1A1 (0.81) | ALDH1A1SMN1; SMN2TDP1GAAPOLB | |
| SCHEMBL13746190 | 0.87 | MAPT (0.61) | ALDH1A1SMN1; SMN2TDP1POLBMAPT | |
| SCHEMBL25045272 | 0.86 | ALDH1A1 (0.65) | ALDH1A1SMN1; SMN2TDP1GAAPOLB | |
| SCHEMBL13746192 | 0.85 | PKM (0.76) | ALDH1A1SMN1; SMN2POLBMAPTTSHR | |
| SCHEMBL5523975 | 0.85 | ALDH1A1 (0.75) | ALDH1A1SMN1; SMN2TDP1GAAPOLB | |
| SCHEMBL12993901 | 0.85 | ALDH1A1 (0.67) | ALDH1A1SMN1; SMN2TDP1TSHRPKM | |
| SCHEMBL8372164 | 0.85 | MEN1 (0.61) | ALDH1A1SMN1; SMN2POLBMAPTTSHR | |
| SCHEMBL17182848 | 0.83 | ALDH1A1 (0.73) | ALDH1A1SMN1; SMN2TDP1GAAPOLB | |
| SCHEMBL17182851 | 0.83 | ALDH1A1 (0.73) | ALDH1A1SMN1; SMN2TDP1GAAPOLB | |
| SCHEMBL17182903 | 0.83 | ALDH1A1 (0.73) | ALDH1A1SMN1; SMN2TDP1GAAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009098282-A1 | LOW MOLECULAR WEIGHT 2,5-DISUBSTITUTED THIOPHENE DERIVATIVES AND USE THEREOF IN THERAPY | NOVASAID AB (SE) | 2009-08-13 | — | — | WO | disclosed |