Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 4/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | ATM | Q13315 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13745505 | 0.79 | RECQL (0.73) | SMN1; SMN2POLBTP53KMT2AMAPT | |
| SCHEMBL21213779 | 0.78 | EPHX2 (0.49) | SMN1; SMN2LMNAKMT2ARAB9A | |
| SCHEMBL20116677 | 0.77 | TAAR1 (0.54) | SMN1; SMN2TAAR1POLBTP53LMNA | |
| SCHEMBL13746186 | 0.77 | NPSR1 (0.72) | POLBMAPT | |
| SCHEMBL29541740 | 0.75 | TAAR1 (0.58) | SMN1; SMN2TAAR1POLBTP53LMNA | |
| SCHEMBL13621122 | 0.75 | CYP2C19 (0.72) | POLBLMNAKMT2AMAPTNPC1 | |
| SCHEMBL21611301 | 0.74 | ALDH1A1 (0.60) | SMN1; SMN2TAAR1POLBTP53MAPT | |
| SCHEMBL28313672 | 0.74 | CHRM4 (0.54) | SMN1; SMN2LMNAKMT2ARAB9A | |
| SCHEMBL1880625 | 0.74 | TACR1 (0.47) | SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL13746185 | 0.73 | CYP2C19 (0.62) | POLBTP53LMNAKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009098282-A1 | LOW MOLECULAR WEIGHT 2,5-DISUBSTITUTED THIOPHENE DERIVATIVES AND USE THEREOF IN THERAPY | NOVASAID AB (SE) | 2009-08-13 | — | — | WO | disclosed |