Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | ME3 | Q16798 | 1/20 | 0.51 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.49 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.49 |
| ▸ | RORC | P51449 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28304541 | 0.80 | POLB (0.59) | SMN1; SMN2LMNARAB9AKMT2AHPGD | |
| SCHEMBL4035778 | 0.80 | NPSR1 (0.70) | CHRM4USP2HPGDEPHX2NPSR1 | |
| SCHEMBL15808499 | 0.78 | KDM4E (0.73) | CHRM4LMNAGAACHRM2KMT2A | |
| SCHEMBL11052233 | 0.77 | GAA (0.64) | SMN1; SMN2LMNAGAAKMT2AUSP2 | |
| SCHEMBL28276627 | 0.77 | GFER (0.50) | CHRM4SMN1; SMN2LMNARAB9ACHRM2 | |
| SCHEMBL1579348 | 0.76 | HSD17B10 (0.52) | SMN1; SMN2LMNAGAARAB9AKMT2A | |
| SCHEMBL21213779 | 0.76 | EPHX2 (0.49) | SMN1; SMN2LMNAGAARAB9AKMT2A | |
| SCHEMBL12425624 | 0.75 | CYP2D6 (0.50) | SMN1; SMN2KMT2AEPHX2CYP2C19 | |
| SCHEMBL26238627 | 0.74 | DRD2 (0.49) | SMN1; SMN2GAAKMT2AHTTNPSR1 | |
| SCHEMBL13745556 | 0.74 | SMN1; SMN2 (0.60) | SMN1; SMN2LMNARAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110177786-A | Pyrazolo [1,5-A] pyridine compounds being substituted are as RET kinase inhibitor | 阿雷生物药品公司 | 2019-08-27 | — | — | CN | disclosed |