Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | CA12 | O43570 | 1/20 | 0.60 |
| ▸ | CA1 | P00915 | 1/20 | 0.60 |
| ▸ | CA2 | P00918 | 1/20 | 0.60 |
| ▸ | CA9 | Q16790 | 1/20 | 0.60 |
| ▸ | TP53 | P04637 | 4/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.56 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5071517 | 0.88 | P2RX7 (0.59) | EPHX2MAPTCA12CA1CA2 | |
| SCHEMBL13746191 | 0.86 | TP53 (0.68) | EPHX2MAPTCA12CA1CA2 | |
| SCHEMBL9202720 | 0.85 | ALDH1A1 (0.51) | EPHX2CA12CA1CA2CA9 | |
| Formic Acid SCHEMBL5085564 | 0.83 | P2RX7 (0.54) | EPHX2MAPTCA12CA1CA2 | |
| SCHEMBL13746180 | 0.82 | CHRM1 (0.59) | EPHX2MAPTCA12CA1CA2 | |
| SCHEMBL13746186 | 0.81 | NPSR1 (0.72) | EPHX2MAPTPOLBALDH1A1TSHR | |
| SCHEMBL5358064 | 0.81 | LMNA (0.57) | EPHX2MAPTCA12CA1CA2 | |
| SCHEMBL4982505 | 0.81 | DRD4 (0.51) | EPHX2MAPTP2RX7ALDH1A1HPGD | |
| SCHEMBL13746189 | 0.81 | ALDH1A1 (0.65) | MAPTTP53POLBRXFP1LMNA | |
| SCHEMBL9198205 | 0.81 | KMT2A (0.57) | EPHX2TP53PLA2G1BPKMATG4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009098282-A1 | LOW MOLECULAR WEIGHT 2,5-DISUBSTITUTED THIOPHENE DERIVATIVES AND USE THEREOF IN THERAPY | NOVASAID AB (SE) | 2009-08-13 | — | — | WO | disclosed |