Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.67 |
| ▸ | TSHR | P16473 | 1/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.65 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.65 |
| ▸ | MAPT | P10636 | 2/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.65 |
| ▸ | TP53 | P04637 | 2/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.61 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.59 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.59 |
| ▸ | GLA | P06280 | 1/20 | 0.59 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8372164 | 0.87 | MEN1 (0.61) | ALDH1A1TSHRLMNASMN1; SMN2CYP3A4 | |
| SCHEMBL12993901 | 0.87 | ALDH1A1 (0.67) | ALDH1A1TSHRLMNASMN1; SMN2CYP3A4 | |
| SCHEMBL13745754 | 0.86 | ALDH1A1 (0.62) | ALDH1A1POLBMEN1KMT2ASLC13A5 | |
| SCHEMBL13746186 | 0.85 | NPSR1 (0.72) | ALDH1A1TSHRMAPTPOLBNPSR1 | |
| SCHEMBL24422954 | 0.84 | ALDH1A1 (0.58) | ALDH1A1TSHRPOLBKMT2ANPSR1 | |
| SCHEMBL7844706 | 0.83 | ALDH1A1 (0.63) | ALDH1A1TSHRLMNASMN1; SMN2CYP3A4 | |
| SCHEMBL13745506 | 0.83 | ALDH1A1 (0.70) | ALDH1A1TSHRLMNASMN1; SMN2MAPT | |
| SCHEMBL13746194 | 0.83 | POLB (0.62) | ALDH1A1LMNAMAPTTP53POLB | |
| SCHEMBL1867735 | 0.83 | NPSR1 (0.53) | ALDH1A1TSHRLMNASMN1; SMN2CYP3A4 | |
| SCHEMBL13061265 | 0.83 | ALDH1A1 (0.62) | ALDH1A1TSHRSMN1; SMN2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009098282-A1 | LOW MOLECULAR WEIGHT 2,5-DISUBSTITUTED THIOPHENE DERIVATIVES AND USE THEREOF IN THERAPY | NOVASAID AB (SE) | 2009-08-13 | — | — | WO | disclosed |