Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | PKM | P14618 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7110355 | 0.88 | HPGD (0.67) | HPGDALDH1A1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL23518203 | 0.85 | KDM4E (0.51) | ALDH1A1LMNASMN1; SMN2MAPTMEN1 | |
| SCHEMBL7562053 | 0.84 | HPGD (0.58) | HPGDALDH1A1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL6013184 | 0.83 | RAB9A (0.64) | HPGDALDH1A1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL16263520 | 0.83 | RAB9A (0.64) | HPGDALDH1A1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL15624559 | 0.82 | HPGD (0.59) | HPGDALDH1A1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL10630944 | 0.81 | ALDH1A1 (0.57) | ALDH1A1LMNARAB9ASMN1; SMN2MEN1 | |
| SCHEMBL10304922 | 0.81 | LMNA (0.71) | HPGDALDH1A1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL31094962 | 0.81 | RAB9A (0.71) | HPGDALDH1A1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL8557641 | 0.80 | LMNA (0.65) | HPGDALDH1A1LMNARAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009097578-A1 | OXIM DERIVATIVES AS HSP90 INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-08-06 | — | — | WO | disclosed |