Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.53 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.53 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.53 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.53 |
| ▸ | CHRNA6 | Q15825 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | STAT3 | P40763 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11772760 | 0.88 | MAPK1 (0.68) | LMNAMAPK1ALDH1A1L3MBTL1HPGD | |
| SCHEMBL24322639 | 0.82 | ALDH1A1 (0.54) | LMNAMAPK1ALDH1A1L3MBTL1HPGD | |
| SCHEMBL1224548 | 0.82 | ALDH1A1 (0.54) | LMNAMAPK1ALDH1A1L3MBTL1HPGD | |
| SCHEMBL13745578 | 0.81 | LMNA (0.68) | LMNAMAPK1ALDH1A1L3MBTL1HPGD | |
| SCHEMBL27109069 | 0.78 | CHRNB2 (0.75) | LMNAALDH1A1HPGDCHRNB2CHRNA3 | |
| SCHEMBL16207607 | 0.78 | CHRNB2 (0.58) | LMNAMAPK1ALDH1A1HPGDCHRNB2 | |
| SCHEMBL25840976 | 0.78 | CHRNB2 (0.58) | LMNAMAPK1ALDH1A1HPGDCHRNB2 | |
| SCHEMBL493454 | 0.78 | CHRNB2 (0.62) | LMNAMAPK1ALDH1A1HPGDCHRNB2 | |
| SCHEMBL1706180 | 0.77 | CHRNB2 (0.87) | ALDH1A1HPGDCHRNB2CHRNA3CHRNA4 | |
| Hydrochloric Acid SCHEMBL2591580 | 0.76 | CHRNB2 (0.60) | LMNAMAPK1ALDH1A1HPGDCHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009098282-A1 | LOW MOLECULAR WEIGHT 2,5-DISUBSTITUTED THIOPHENE DERIVATIVES AND USE THEREOF IN THERAPY | NOVASAID AB (SE) | 2009-08-13 | — | — | WO | disclosed |