SCHEMBL7121279

SCHEMBL7121279

CC(C)(C)c1ccc(Oc2cccc(C#N)c2C#N)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.51
GAA P10253 1/20 0.51
SMN1; SMN2 Q16637 2/20 0.51
KDM4E B2RXH2 1/20 0.51
HPGD P15428 3/20 0.46
ALDH1A1 P00352 2/20 0.46
NPSR1 Q6W5P4 2/20 0.46
LMNA P02545 1/20 0.46
MAPT P10636 3/20 0.42
NPC1 O15118 1/20 0.42
MAPK1 P28482 1/20 0.42
RAB9A P51151 1/20 0.42
AR P10275 7/20 0.39
KIF11 P52732 1/20 0.39
MAPK14 Q16539 1/20 0.39
RECQL P46063 1/20 0.38
TLR8 Q9NR97 2/20 0.38
HSD11B1 P28845 1/20 0.37
FNTA P49354 1/20 0.37
FNTB P49356 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29800655 1.00 POLB (0.51) POLBGAASMN1; SMN2KDM4EHPGD
SCHEMBL1374728 0.92 SMN1; SMN2 (0.50) POLBGAASMN1; SMN2KDM4EHPGD
SCHEMBL16638707 0.87 POLB (0.68) POLBGAASMN1; SMN2KDM4EHPGD
SCHEMBL7113698 0.87 FNTA (0.49) POLBGAASMN1; SMN2KDM4EALDH1A1
SCHEMBL28587818 0.86 SMN1; SMN2 (0.46) POLBGAASMN1; SMN2KDM4EHPGD
SCHEMBL12732871 0.85 POLB (0.49) POLBGAASMN1; SMN2KDM4EHPGD
SCHEMBL9745713 0.85 KDM4E (0.49) POLBGAASMN1; SMN2KDM4EAR
SCHEMBL8975487 0.84 POLB (0.73) POLBGAASMN1; SMN2KDM4EALDH1A1
SCHEMBL1374637 0.84 KDM4E (0.48) POLBGAASMN1; SMN2KDM4EAR
SCHEMBL12731800 0.83 HPGD (0.45) POLBGAASMN1; SMN2KDM4EHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113136112-B Near infrared absorbing dyes of broad spectral band 上海昀通电子科技有限公司 2023-04-28 CN disclosed
CN-110461814-B Resin blends, prepregs and articles containing a phthalonitrile reactive diluent and a bisphthalonitrile resin 3M创新有限公司 2023-04-14 CN disclosed
US-20220386724-A1 ANTIMICROBIAL DYES FOR HEALTHCARE APPAREL BMG (BRITISH MEDICAL GROUP) LIMITED (GB) 2022-12-08 US disclosed
CN-114555881-A Antimicrobial dye for medical and health-care clothing 化学智能公司 2022-05-27 CN disclosed
US-11292891-B2 Resin blends containing a phthalonitrile reactive diluent and a diphthalonitrile resin, prepregs, and articles 3M INNOVATIVE PROPERTIES COMPANY (US) 2022-04-05 US disclosed
CN-113136112-A Near infrared absorbing dye with wide spectral band 上海昀通电子科技有限公司 2021-07-20 CN disclosed
WO-2021001445-A1 ANTIMICROBIAL DYES FOR HEALTHCARE APPAREL CHEMICAL INTELLIGENCE LIMITED (GB) 2021-01-07 WO disclosed
US-20200131336-A1 RESIN BLENDS CONTAINING A PHTHALONITRILE REACTIVE DILUENT AND A DIPHTHALONITRILE RESIN, PREPREGS, AND ARTICLES 3M INNOVATIVE PROPERTIES COMPANY 2020-04-30 US disclosed
EP-3601215-A1 RESIN BLENDS CONTAINING A PHTHALONITRILE REACTIVE DILUENT AND A DIPHTHALONITRILE RESIN, PREPREGS, AND ARTICLES 3M Innovative Properties Company (US) 2020-02-05 EP disclosed
WO-2018175025-A1 RESIN BLENDS CONTAINING A PHTHALONITRILE REACTIVE DILUENT AND A DIPHTHALONITRILE RESIN, PREPREGS, AND ARTICLES 3M INNOVATIVE PROPERTIES COMPANY (US) 2018-09-27 WO disclosed
EP-0675489-B1 Optical recording medium TDK CORP (JP) 2003-11-12 EP disclosed
US-5776656-A MULTILAYER WITH DIFFERENT OPTICAL CONSTANTS, CYANINE DYES, COMPLEX INDEX OF REFRACTION TDK CORPORATION (JP) 1998-07-07 US disclosed
US-5679430-A RECORDING LAYER COMPRISES TWO DYES HAVING DIFFERING REFRACTIVE INDICES; CAPABLE OF WRITING AND READING AT SHORT WAVELENGTH AS WELL AS AT CONVENTIONAL WAVELENGTH TDK CORPORATION (JP) 1997-10-21 US disclosed
US-5569504-A WRITE ONCE DISK, PHTHALOCYANINE DYE TDK CORPORATION (JP) 1996-10-29 US disclosed
EP-0675489-A1 Optical recording medium TDK Corporation (JP) 1995-10-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200131336-A1 RESIN BLENDS CONTAINING A PHTHALONITRILE REACTIVE DILUENT AND A DIPHTHALONITRILE RESIN, PREPREGS, AND ARTICLES PNN, RPN1, DCXR POLB 1900/4885GAA 2465/4885SMN1; SMN2 2650/4885
US-11292891-B2 Resin blends containing a phthalonitrile reactive diluent and a diphthalonitrile resin, prepregs, and articles PNN, RPN1, DCXR POLB 1900/4885GAA 2465/4885SMN1; SMN2 2650/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.