Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR3 | P25089 | 2/20 | 0.31 |
| ▸ | FPR2 | P25090 | 2/20 | 0.31 |
| ▸ | ESRRB | O95718 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | ESRRA | P11474 | 1/20 | 0.31 |
| ▸ | ESRRG | P62508 | 1/20 | 0.31 |
| ▸ | RORC | P51449 | 2/20 | 0.31 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.30 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10182415 | 1.00 | FPR3 (0.31) | FPR3FPR2ESRRBESR1ESRRA | |
| SCHEMBL10182263 | 0.80 | NPC1 (0.46) | FPR3FPR2 | |
| SCHEMBL19488759 | 0.79 | NPC1 (0.43) | FPR3FPR2 | |
| SCHEMBL10182417 | 0.78 | KMT2A (0.41) | — | |
| SCHEMBL12752017 | 0.78 | KMT2A (0.41) | — | |
| SCHEMBL15586735 | 0.78 | KMT2A (0.41) | — | |
| SCHEMBL15773712 | 0.78 | KMT2A (0.41) | — | |
| SCHEMBL19488754 | 0.73 | FPR2 (0.38) | FPR3FPR2 | |
| SCHEMBL10202447 | 0.73 | FPR2 (0.38) | FPR3FPR2 | |
| SCHEMBL1294187 | 0.72 | ALDH1A1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009102633-A1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2009-08-20 | — | — | WO | disclosed |