SCHEMBL13747192

SCHEMBL13747192

C=C1CC(NCCCC)CC(C)(C)N1OC(C)=O

nearest known ligand 0.35

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
FLT3 P36888 1/20 0.31
TYRO3 Q06418 1/20 0.31
MERTK Q12866 1/20 0.31
GAS6 Q14393 1/20 0.31
TSHR P16473 1/20 0.30
S1PR4 O95977 1/20 0.30
S1PR1 P21453 1/20 0.30
S1PR3 Q99500 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13748274 0.89
SCHEMBL14224277 0.80
SCHEMBL4023767 0.78 TSHR (0.43) TSHRS1PR4S1PR1S1PR3
Hydrochloric Acid SCHEMBL9400298 0.77 TSHR (0.42) TSHRS1PR4S1PR1S1PR3
SCHEMBL13483861 0.75
SCHEMBL14066587 0.73 NAAA (0.45)
SCHEMBL13747657 0.71 TSHR (0.44) TSHR
SCHEMBL9164073 0.70 S1PR4 (0.37) FLT3TYRO3MERTKGAS6S1PR4
SCHEMBL4026717 0.69 TSHR (0.45) TSHRS1PR4S1PR1S1PR3
SCHEMBL14066744 0.68 KMT2A (0.42) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7579411-B2 Process for the controlled increase in the molecular weight of polyethylenes CIBA SPECIALTY CHEMICALS CORPORATION (US) 2009-08-25 US disclosed
US-20080146740-A1 Process for the controlled increase in the molecular weight of polyethylenes ROTH MICHAEL 2008-06-19 US disclosed