Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.30 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14066587 | 0.81 | NAAA (0.45) | KMT2AMEN1GAA | |
| SCHEMBL14066744 | 0.81 | KMT2A (0.42) | TSHRKMT2AALDH1A1ESR1HSD17B10 | |
| SCHEMBL12829912 | 0.81 | KMT2A (0.43) | TSHRKMT2AALDH1A1ESR1HSD17B10 | |
| SCHEMBL14066739 | 0.77 | TSHR (0.30) | TSHRKMT2A | |
| SCHEMBL1138567 | 0.72 | KMT2A (0.63) | TSHRKMT2AALDH1A1ESR1HSD17B10 | |
| SCHEMBL13245888 | 0.72 | TSHR (0.35) | TSHRKMT2AALDH1A1ESR1HSD17B10 | |
| SCHEMBL12829913 | 0.71 | CYP2D6 (0.33) | TSHRKMT2AGAA | |
| SCHEMBL13747192 | 0.71 | FLT3 (0.31) | TSHR | |
| SCHEMBL14224298 | 0.71 | — | — | |
| SCHEMBL15987036 | 0.70 | KMT2A (0.54) | TSHRKMT2AALDH1A1ESR1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7579411-B2 | Process for the controlled increase in the molecular weight of polyethylenes | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2009-08-25 | — | — | US | disclosed |
| US-20080146740-A1 | Process for the controlled increase in the molecular weight of polyethylenes | ROTH MICHAEL | 2008-06-19 | — | — | US | disclosed |