SCHEMBL1374756

SCHEMBL1374756

CNc1ccc2c(O)cc(S(=O)(=O)O)cc2c1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRMT1 Q99873 2/20 0.70
CASP6 P55212 5/20 0.62
NSD2 O96028 3/20 0.62
DUSP3 P51452 2/20 0.62
PTPN5 P54829 2/20 0.62
PTPN11 Q06124 2/20 0.62
CTDSP1 Q9GZU7 1/20 0.58
NT5E P21589 3/20 0.57
CASP7 P55210 1/20 0.57
SIRT1 Q96EB6 1/20 0.51
SNCA P37840 2/20 0.45
ALDH1A1 P00352 2/20 0.44
HSD17B10 Q99714 2/20 0.44
TP53 P04637 1/20 0.44
CYP3A4 P08684 1/20 0.44
THRB P10828 1/20 0.44
HPGD P15428 1/20 0.44
ALOX15 P16050 1/20 0.44
CASP1 P29466 1/20 0.44
RECQL P46063 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL37480409 1.00 PRMT1 (0.70) PRMT1CASP6NSD2DUSP3PTPN5
SCHEMBL9776574 0.98 PRMT1 (0.68) PRMT1CASP6NSD2DUSP3PTPN5
SCHEMBL18270519 0.90 PRMT1 (0.61) PRMT1CASP6NSD2DUSP3PTPN5
SCHEMBL4651295 0.90 CASP6 (0.69) PRMT1CASP6NSD2DUSP3PTPN5
SCHEMBL30213847 0.87 PRMT1 (0.74) PRMT1CASP6NSD2DUSP3PTPN5
SCHEMBL9236771 0.87 PRMT1 (0.74) PRMT1CASP6NSD2DUSP3PTPN5
SCHEMBL3831401 0.86 PRMT1 (0.58) PRMT1CASP6NSD2DUSP3PTPN5
SCHEMBL27846700 0.84 PRMT1 (0.72) PRMT1CASP6NSD2DUSP3PTPN5
SCHEMBL29462031 0.84 CASP6 (0.77) PRMT1CASP6NSD2DUSP3PTPN5
SCHEMBL465086 0.84 CASP6 (0.77) PRMT1CASP6NSD2DUSP3PTPN5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 298 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117186666-A High-fastness black acid metal complex dye and preparation method thereof 浙江亿得新材料股份有限公司 2023-12-08 CN claimed
WO-2013008201-A2 NOVEL REACTIVE DYES, THERE MIXTURES AND PROCESSES THEREOF COLOURTEX INDUSTRIES LIMITED (IN) 2013-01-17 WO claimed
US-7105645-B2 Water-soluble fiber-reactive dyes, method for the production and use thereof DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 2006-09-12 US claimed
US-20050198748-A1 Copper complexes of monoazo dyes; diazotization of a sulfonyl-o-hydroxyaniline, coupling to a 1-hydroxy-3-sulfonate-6-aminonaphthalene, coppering with copper sulfate pentahydrate; improved washfastness, photostability, and compatibility with other dyes which fix at lower temperatures DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 2005-09-15 US claimed
EP-0579207-B1 Charge control agent and positively chargeable toner for developing electrostatic images ORIENT CHEMICAL IND (JP) 1998-01-07 EP claimed
US-5407774-A Charge control agent and positively chargeable toner for developing electrostatic images ORIENT CHEMICAL INDUSTRIES, LTD. (JP) 1995-04-18 US claimed
EP-0579207-A1 Charge control agent and positively chargeable toner for developing electrostatic images ORIENT CHEMICAL INDUSTRIES, LTD. (JP) 1994-01-19 EP claimed
US-4376737-A Process for the production of naphthylaminehydroxysulphonic acids CIBA-GEIGY AG (CH) 1983-03-15 US claimed
US-4163675-A CONTAINING NAPHTHALENE DERIVATIVES PILOT INK CO., LTD. (JP) 1979-08-07 US claimed
CN-116018381-B Polarizing film, polarizing plate and liquid crystal display device containing azo compound or salt thereof 日本化药株式会社 2025-05-02 CN disclosed
WO-2024043261-A1 AZO COMPOUND OR SALT THEREOF, AND POLARIZING FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE COMPRISING SAME 日本化薬株式会社 2024-02-29 WO disclosed
US-11872236-B2 Pharmacological agents for treating ocular diseases CALASIA PHARMACEUTICALS, INC. (US) 2024-01-16 US disclosed
US-11872236-B2 Pharmacological agents for treating ocular diseases CALASIA PHARMACEUTICALS, INC. (US) 2024-01-16 US disclosed
CN-117186666-A High-fastness black acid metal complex dye and preparation method thereof 浙江亿得新材料股份有限公司 2023-12-08 CN disclosed
US-4052386-A REACTIVE PHTHALOCYANINE DYESTUFFS CONTAINING A FLUOROPYRIMIDINYL GROUP BAYER AKTIENGESELLSCHAFT (DT) 1977-10-04 US disclosed
US-4033944-A Fibre-reactive hydroxycycloalkenyl-halo triazinyl containing dyestuffs CIBA-GEIGY CORPORATION (US) 1977-07-05 US disclosed
US-4007164-A FIBER-REACTIVE, CELLULOSE, WOOL BAYER AKTIENGESELLSCHAFT (DT) 1977-02-08 US disclosed
US-3971738-A Heavy metal complexes of azo compounds containing a halogeno-2,3-dihydroxy pyridine coupling component CIBA-GEIGY AG (CH) 1976-07-27 US disclosed
US-3947407-A ANTHRAQUINONE DYE CIBA-GEIGY AG (CH) 1976-03-30 US disclosed
US-3933785-A Azo compounds CIBA-GEIGY AG (CH) 1976-01-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11872236-B2 Pharmacological agents for treating ocular diseases CRYAA, CRYAB, TTR PRMT1 4742/4885CASP6 1975/4885NSD2 4831/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.