Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | MAP3K11 | Q16584 | 1/20 | 0.36 |
| ▸ | CALCA | P06881 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29388502 | 0.90 | MAP3K11 (0.39) | MAP3K11 | |
| SCHEMBL30748859 | 0.87 | MAP3K11 (0.43) | MAP3K11 | |
| SCHEMBL30748975 | 0.87 | MAP3K11 (0.46) | MAP3K11 | |
| SCHEMBL30749023 | 0.85 | MAP3K11 (0.45) | MAP3K11 | |
| SCHEMBL15935920 | 0.80 | FGFR1 (0.38) | MAP3K11CALCA | |
| SCHEMBL15117493 | 0.76 | MAP3K11 (0.41) | BACE1MAP3K11CALCAOPRM1 | |
| SCHEMBL31349435 | 0.75 | MAP3K11 (0.42) | BACE1MAP3K11CALCAOPRM1 | |
| SCHEMBL13748033 | 0.75 | — | — | |
| SCHEMBL15699563 | 0.75 | MAP3K11 (0.42) | BACE1MAP3K11CALCAOPRM1 | |
| SCHEMBL550356 | 0.74 | CALCA (0.50) | BACE1CALCAOPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009105348-A1 | IMIDAZOBENZAZEPINE CGRP RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 2009-08-27 | — | — | WO | disclosed |