Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.30 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.30 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL588784 | 0.77 | GABRA1 (0.39) | GABRA1GABRB2CA1CA2HPGD | |
| SCHEMBL19016906 | 0.75 | SLC6A2 (0.40) | GABRA1GABRB2CA1CA2HPGD | |
| SCHEMBL23489934 | 0.75 | SLC6A2 (0.40) | GABRA1GABRB2CA1CA2HPGD | |
| SCHEMBL25742652 | 0.72 | ALDH1A1 (0.40) | CA1CA2CA12CA4CA7 | |
| SCHEMBL172361 | 0.71 | ACHE (0.39) | CA1CA2HPGDCA12CA4 | |
| SCHEMBL5101318 | 0.71 | GABRA1 (0.50) | GABRA1GABRB2CA1CA2HPGD | |
| SCHEMBL5101317 | 0.71 | GABRA1 (0.50) | GABRA1GABRB2CA1CA2HPGD | |
| SCHEMBL382010 | 0.71 | GABRA1 (0.50) | GABRA1GABRB2CA1CA2HPGD | |
| SCHEMBL12285092 | 0.69 | MAPT (0.50) | CA1CA2HPGDCA12CA4 | |
| SCHEMBL7550549 | 0.69 | GABRA1 (0.37) | GABRA1GABRB2CA1CA2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090209046-A1 | Neutral Pharmaceuticals | MOULTON BRIAN DOUGLAS | 2009-08-20 | — | — | US | disclosed |