SCHEMBL13752168

SCHEMBL13752168

CC(=O)N(C)c1nc(N(C)C(C)=O)nc(N(C)C(C)=O)n1

nearest known ligand 0.43

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.43
SMN1; SMN2 Q16637 5/20 0.41
TSHR P16473 1/20 0.41
LMNA P02545 2/20 0.40
CYP1A2 P05177 1/20 0.40
THRB P10828 1/20 0.40
BLM P54132 1/20 0.40
CREBBP Q92793 1/20 0.40
HSD17B10 Q99714 1/20 0.40
ALDH1A1 P00352 6/20 0.37
KDM4E B2RXH2 1/20 0.37
HTT P42858 1/20 0.35
ELANE P08246 1/20 0.35
FSCN1 Q16658 1/20 0.34
RAB9A P51151 2/20 0.34
NPC1 O15118 1/20 0.34
HPGD P15428 1/20 0.33
TSPO P30536 1/20 0.31
MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9132750 0.92 LMNA (0.55) POLBSMN1; SMN2TSHRLMNACYP1A2
SCHEMBL20063064 0.86 POLB (0.48) POLBSMN1; SMN2TSHRLMNACYP1A2
SCHEMBL30299626 0.81 SMN1; SMN2 (0.44) SMN1; SMN2TSHRHSD17B10ALDH1A1HTT
SCHEMBL3136168 0.77 HSD17B10 (0.40) POLBSMN1; SMN2TSHRLMNACYP1A2
SCHEMBL30299648 0.76 ALDH1A1 (0.45) POLBSMN1; SMN2TSHRLMNACYP1A2
SCHEMBL4365313 0.73 KMT2A (0.41) POLBSMN1; SMN2LMNACYP1A2THRB
SCHEMBL19454935 0.71 ALDH1A1 (0.41) POLBSMN1; SMN2TSHRCYP1A2HSD17B10
SCHEMBL2471662 0.70 CYP3A4 (0.43) POLBSMN1; SMN2TSHRLMNACYP1A2
SCHEMBL3641200 0.70 TSHR (0.43) POLBSMN1; SMN2TSHRLMNACYP1A2
SCHEMBL568378 0.69 ALDH1A1 (0.39) POLBSMN1; SMN2TSHRLMNACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7576036-B2 Heat-sensitive recording material, heat-sensitive recording method and method for manufacturing heat-sensitive recording material FUJIFILM CORPORATION (JP) 2009-08-18 US disclosed
US-20070032381-A1 Heat-sensitive recording material, heat-sensitive recording method and method for manufacturing heat-sensitive recording material FUJI PHOTO FILM CO., LTD. 2007-02-08 US disclosed
US-20070004594-A1 Heat-sensitive recording material and heat-sensitive recording method FUJI PHOTO FILM CO., LTD. 2007-01-04 US disclosed