Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 8/20 | 0.50 |
| ▸ | MAPT | P10636 | 8/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | RECQL | P46063 | 5/20 | 0.50 |
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | MAOA | P21397 | 4/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | USP2 | O75604 | 3/20 | 0.50 |
| ▸ | APEX1 | P27695 | 2/20 | 0.50 |
| ▸ | THRB | P10828 | 2/20 | 0.50 |
| ▸ | BRCA1 | P38398 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | RAF1 | P04049 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dioncoquinone B SCHEMBL3401149 | 0.84 | MEN1 (0.60) | MEN1MAPTKMT2AKDM4EALDH1A1 | |
| SCHEMBL7154751 | 0.75 | MAPT (0.69) | MEN1MAPTKMT2AKDM4EALDH1A1 | |
| SCHEMBL16088854 | 0.74 | MAPT (0.73) | MEN1MAPTKMT2AKDM4EALDH1A1 | |
| SCHEMBL2772226 | 0.72 | MAPT (0.86) | MEN1MAPTKMT2AKDM4EALDH1A1 | |
| SCHEMBL6904748 | 0.71 | MAPT (0.83) | MEN1MAPTKMT2AKDM4EALDH1A1 | |
| SCHEMBL29359549 | 0.71 | ELANE (0.70) | MEN1MAPTKMT2AKDM4EALDH1A1 | |
| SCHEMBL10909836 | 0.71 | ELANE (0.70) | MEN1MAPTKMT2AKDM4EALDH1A1 | |
| SCHEMBL30432375 | 0.71 | ELANE (0.70) | MEN1MAPTKMT2AKDM4EALDH1A1 | |
| SCHEMBL14213384 | 0.70 | MEN1 (0.61) | MEN1MAPTKMT2AKDM4EALDH1A1 | |
| SCHEMBL12846567 | 0.69 | MAPT (0.41) | MEN1MAPTKMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2093207-A1 | Antiinfective and antitumoral compounds isolated from tropical lianas | Julius-Maximilians-Universität Würzburg (DE) | 2009-08-26 | — | — | EP | disclosed |