Dioncoquinone B

Dioncoquinone B

SCHEMBL3401149

CC1=C(O)C(=O)c2c(ccc(O)c2O)C1=O

nearest known ligand 0.60

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 8/20 0.60
▸ MAPT P10636 8/20 0.60
▸ KMT2A Q03164 8/20 0.60
▸ ALDH1A1 P00352 6/20 0.60
▸ KDM4E B2RXH2 5/20 0.60
▸ RECQL P46063 5/20 0.60
▸ MAPK1 P28482 5/20 0.60
▸ HPGD P15428 4/20 0.60
▸ MAOA P21397 4/20 0.60
▸ CYP3A4 P08684 3/20 0.60
▸ ALOX15 P16050 3/20 0.60
▸ HSD17B10 Q99714 3/20 0.60
▸ THRB P10828 3/20 0.60
▸ TDP1 Q9NUW8 3/20 0.60
▸ APEX1 P27695 2/20 0.60
▸ USP2 O75604 2/20 0.60
▸ RAF1 P04049 2/20 0.60
▸ TP53 P04637 2/20 0.60
▸ MAP2K1 Q02750 2/20 0.60
▸ CSNK2A2 P19784 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12846567 0.85 MAPT (0.41) MEN1MAPTKMT2AALDH1A1KDM4E
SCHEMBL13752254 0.84 MEN1 (0.50) MEN1MAPTKMT2AALDH1A1KDM4E
SCHEMBL7154751 0.84 MAPT (0.69) MEN1MAPTKMT2AALDH1A1KDM4E
SCHEMBL2772226 0.81 MAPT (0.86) MEN1MAPTKMT2AALDH1A1KDM4E
SCHEMBL19452222 0.80 MAPT (0.56) MEN1MAPTKMT2AALDH1A1KDM4E
SCHEMBL6904748 0.79 MAPT (0.83) MEN1MAPTKMT2AALDH1A1KDM4E
SCHEMBL13752255 0.79 STAT3 (0.37) MEN1MAPTKMT2AALDH1A1KDM4E
SCHEMBL19449186 0.79 MAPT (0.53) MEN1MAPTKMT2AALDH1A1KDM4E
SCHEMBL10909836 0.78 ELANE (0.70) MEN1MAPTKMT2AALDH1A1KDM4E
SCHEMBL30432375 0.78 ELANE (0.70) MEN1MAPTKMT2AALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3782649-B1 BIODEGRADABLE POLYETHYLENE GLYCOL BASED WATER-INSOLUBLE HYDROGELS ASCENDIS PHARMA AS (DK) 2025-05-14 — — EP disclosed
US-20230381323-A1 RELEASABLE CONJUGATES FISH & RICHARDSON PC 2023-11-30 — — US disclosed
US-11786599-B2 Releasable conjugates QUIAPEG PHARMACEUTICALS AB (SE) 2023-10-17 — — US disclosed
US-20230123784-A1 Biodegradable Polyethylene Glycol Based Water-Insoluble Hydrogels ASCENDIS PHARMA A/S (DK) 2023-04-20 — — US disclosed
US-11559482-B2 Biodegradable polyethylene glycol based water-insoluble hydrogels ASCENDIS PHARMA A/S (DE) 2023-01-24 — — US disclosed
EP-4011396-A1 RELEASABLE CONJUGATES QuiaPEG Pharmaceuticals AB (SE) 2022-06-15 — — EP disclosed
EP-2252569-B1 ANTIINFECTIVE AND ANTITUMORAL COMPOUNDS ISOLATED FROM TROPICAL LIANAS JULIUS MAXIMILIANS UNIVERSITÄT WÜRZBURG (DE) 2016-10-05 — — EP disclosed
EP-2252569-B1 ANTIINFECTIVE AND ANTITUMORAL COMPOUNDS ISOLATED FROM TROPICAL LIANAS JULIUS MAXIMILIANS UNIVERSITÄT WÜRZBURG (DE) 2016-10-05 — — EP disclosed
US-8877718-B2 Antiinfective and antitumoral compounds isolated from tropical lianas JULIUS-MAXIMILIANS-UNIVERSITÄT WÜRZBURG (DE) 2014-11-04 — — US disclosed
US-8877718-B2 Antiinfective and antitumoral compounds isolated from tropical lianas JULIUS-MAXIMILIANS-UNIVERSITÄT WÜRZBURG (DE) 2014-11-04 — — US disclosed
US-8877718-B2 Antiinfective and antitumoral compounds isolated from tropical lianas JULIUS-MAXIMILIANS-UNIVERSITÄT WÜRZBURG (DE) 2014-11-04 — — US disclosed
US-20110059911-A1 Antiinfective and Antitumoral Compounds Isolated From Tropical Lianas JULIUS-MAXIMILIANS-UNIVERSITAT WURZBURG (DE) 2011-03-10 — — US disclosed
US-20110059911-A1 Antiinfective and Antitumoral Compounds Isolated From Tropical Lianas JULIUS-MAXIMILIANS-UNIVERSITAT WURZBURG (DE) 2011-03-10 — — US disclosed
US-20110059911-A1 Antiinfective and Antitumoral Compounds Isolated From Tropical Lianas JULIUS-MAXIMILIANS-UNIVERSITAT WURZBURG (DE) 2011-03-10 — — US disclosed
EP-2252569-A2 ANTIINFECTIVE AND ANTITUMORAL COMPOUNDS ISOLATED FROM TROPICAL LIANAS Julius-Maximilians-Universität Würzburg (DE) 2010-11-24 — — EP disclosed
EP-2093207-A1 Antiinfective and antitumoral compounds isolated from tropical lianas Julius-Maximilians-Universität Würzburg (DE) 2009-08-26 — — EP disclosed
EP-2093207-A1 Antiinfective and antitumoral compounds isolated from tropical lianas Julius-Maximilians-Universität Würzburg (DE) 2009-08-26 — — EP disclosed
WO-2009098082-A2 ANTIINFECTIVE AND ANTITUMORAL COMPOUNDS ISOLATED FROM TROPICAL LIANAS JULIUS-MAXIMILIANS-UNIVERSITÄT WÜRZBURG (DE) 2009-08-13 — — WO disclosed
WO-2009098082-A2 ANTIINFECTIVE AND ANTITUMORAL COMPOUNDS ISOLATED FROM TROPICAL LIANAS JULIUS-MAXIMILIANS-UNIVERSITÄT WÜRZBURG (DE) 2009-08-13 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110059911-A1 Antiinfective and Antitumoral Compounds Isolated From Tropical Lianas NCL, SYNCRIP, MYC MEN1 2620/4885MAPT 4212/4885KMT2A 3017/4885
US-20230123784-A1 Biodegradable Polyethylene Glycol Based Water-Insoluble Hydrogels PLG, PHYKPL, PLOD3 MEN1 4821/4885MAPT 1671/4885KMT2A 3136/4885
US-20230381323-A1 RELEASABLE CONJUGATES GUSB, ABCB11, UGT2B7 MEN1 2694/4885MAPT 3354/4885KMT2A 4144/4885
US-11559482-B2 Biodegradable polyethylene glycol based water-insoluble hydrogels PLG, PHYKPL, PLOD3 MEN1 4821/4885MAPT 1671/4885KMT2A 3136/4885
US-11786599-B2 Releasable conjugates GUSB, ABCB11, UGT2B7 MEN1 2694/4885MAPT 3354/4885KMT2A 4144/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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